Prostaglandin E2 receptor subtype 2 (EP2) regulates microglial activation and associated neurotoxicity induced by aggregated α-synuclein

被引：0
|
作者：
Jinghua Jin
Feng-Shiun Shie
Jun Liu
Yan Wang
Jeanne Davis
Aimee M Schantz
Kathleen S Montine
Thomas J Montine
Jing Zhang
机构：
[1] University of Washington School of Medicine,Department of Pathology
来源：
Journal of Neuroinflammation | / 4卷
关键词：
Substantia Nigra; Microglial Activation; Lewy Body Disease; Nicotinamide Adenine Dinucleotide Phosphate; MPTP Treatment;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [1] Prostaglandin E2 receptor subtype 2 (EP2) regulates microglial activation and associated neurotoxicity induced by aggregated α-synuclein
    Jin, Jinghua
    Shie, Feng-Shiun
    Liu, Jun
    Wang, Yan
    Davis, Jeanne
    Schantz, Aimee M.
    Montine, Kathleen S.
    Montine, Thomas J.
    Zhang, Jing
    JOURNAL OF NEUROINFLAMMATION, 2007, 4 (1)
  • [2] Molecular cloning and expression of a rat prostaglandin E2 receptor of the EP2 subtype
    Nemoto, K
    Pilbeam, CC
    Bilak, SR
    Raisz, LG
    PROSTAGLANDINS & OTHER LIPID MEDIATORS, 1997, 54 (04): : 713 - 725
  • [3] Ligand recognition, unconventional activation, and G protein coupling of the prostaglandin E2 receptor EP2 subtype
    Qu, Changxiu
    Mao, Chunyou
    Xiao, Peng
    Shen, Qingya
    Zhong, Ya-Ni
    Yang, Fan
    Shen, Dan-Dan
    Tao, Xiaona
    Zhang, Huibing
    Yan, Xu
    Zhao, Ru-Jia
    He, Junyan
    Guan, Ying
    Zhang, Chao
    Hou, Guihua
    Zhang, Peng-Ju
    Hou, Guige
    Li, Zijian
    Yu, Xiao
    Chai, Ren-Jie
    Guan, You-Fei
    Sun, Jin-Peng
    Zhang, Yan
    SCIENCE ADVANCES, 2021, 7 (14):
  • [4] Selective activation of the prostaglandin E2 receptor subtype EP2 or EP4 leads to inhibition of platelet aggregation
    Kuriyama, Shuhko
    Kashiwagi, Hitoshi
    Yuhki, Koh-ichi
    Kojima, Fumiaki
    Yamada, Takehiro
    Fujino, Takayuki
    Hara, Akiyoshi
    Takayama, Koji
    Maruyama, Takayuki
    Yoshida, Akitoshi
    Narumiya, Shuh
    Ushikubi, Fumitaka
    THROMBOSIS AND HAEMOSTASIS, 2010, 104 (04) : 796 - 803
  • [5] Selective activation of the prostaglandin E2 receptor subtype EP2 or EP4 leads to an inhibition of platelet aggregation
    Kashiwagi, Hitoshi
    Kuriyama, Shuhko
    Yuhki, Koh-ichi
    Ushikubi, Fumitaka
    JOURNAL OF PHARMACOLOGICAL SCIENCES, 2009, 109 : 62P - 62P
  • [6] Prostaglandin E2 Receptor Subtype EP2 as a Target for High-Risk Neuroblastoma
    Hou, R.
    Yu, Y.
    Jiang, J.
    PEDIATRIC BLOOD & CANCER, 2021, 68 : S222 - S222
  • [7] Potential mechanisms for an invasion suppressor function for the EP2 subtype of prostaglandin E2 receptor
    Konger, RL
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2005, 124 (04) : A21 - A21
  • [8] Effect of deletion of the prostaglandin EP2 receptor on the anabolic response to prostaglandin E2 and a selective EP2 receptor agonist
    Choudhary, Shilpa
    Alander, Cynthia
    Zhan, Peili
    Gao, Qi
    Pilbeam, Carol
    Raisz, Lawrence
    PROSTAGLANDINS & OTHER LIPID MEDIATORS, 2008, 86 (1-4) : 35 - 40
  • [9] Heterodimerization of the prostaglandin E2 receptor EP2 and the calcitonin receptor CTR
    Matsubara, Shin
    Shiraishi, Akira
    Sakai, Tsubasa
    Okuda, Toshimi
    Satake, Honoo
    PLOS ONE, 2017, 12 (11):
  • [10] Prostaglandin E2 and Its Receptor EP2 Modulate Macrophage Activation and Fusion in Vitro
    Saleh, Leila S.
    Vanderheyden, Casey
    Frederickson, Andrew
    Bryant, Stephanie J.
    ACS BIOMATERIALS SCIENCE & ENGINEERING, 2020, 6 (05) : 2668 - 2681
12345