Effect of Sodium Bicarbonate Amount on In Vitro Indomethacin Release from Self-Setting Carbonated-Apatite Cement

被引：0
|
作者：
Makoto Otsuka
Yoshihisa Matsuda
Zeren Wang
Jeffrey L. Fox
William I. Higuchi
机构：
[1] Kobe University,Department of Pharmaceutical Technology
[2] University of Utah,Department of Pharmaceutics and Pharmaceutical Chemistry
来源：
Pharmaceutical Research | 1997年 / 14卷
关键词：
drug delivery system; biomaterials; self-setting bioactive carbonate apatite cement; indomethacin release; mercury porosimetry;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Purpose. In the present study, to develop a drug delivery system with higher bioacitivity in hard tissues by using the self-setting bioactive carbonate apatite cement, we have investigated the effects of sodium bicarbonate content on thein vitro drug release from a self-setting bioactive carbonate apatite cement containing indomethacin (IMC).
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页码：444 / 449
页数：5
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