Change in Alcohol Use Based on Self-Report and a Quantitative Biomarker, Phosphatidylethanol, in People With HIV

被引：0

作者：

Kathleen A. McGinnis

Janet P. Tate

Kendall J. Bryant

Amy C. Justice

Patrick G. O’Connor

Maria C. Rodriguez-Barradas

Stephen Crystal

Christopher J. Cutter

Nathan B. Hansen

Stephen A. Maisto

Vincent C. Marconi

Emily C. Williams

Robert L. Cook

Adam J. Gordon

Kirsha S. Gordon

Oghenowede Eyawo

E. Jennifer Edelman

David A. Fiellin

机构：

[1] VA Connecticut Healthcare System,Infectious Diseases Section, Michael E. DeBakey VAMC and Department of Medicine

[2] US Department of Veterans Affairs,Institute for Health, Health Care Policy and Aging Research

[3] Yale School of Medicine,College of Public Health

[4] National Institute on Alcohol Abuse and Alcoholism,Department of Psychology

[5] Baylor College of Medicine,School of Medicine and Rollins School of Public Health

[6] Rutgers University,Department of Health Systems and Population Health, University of Washington School of Public Health and Seattle

[7] University of Georgia,Denver Health Services Research & Development Center of Innovation for Veteran

[8] Syracuse University,Centered and Value

[9] Emory University,Driven Care

[10] Atlanta Veterans Affairs Medical Center,Department of Epidemiology

[11] VA Puget Sound Healthcare System,School of Global Health

[12] University of Florida,Center for Interdisciplinary Research On AIDS

[13] University of Utah and Salt Lake City VA Health Care System,undefined

[14] York University,undefined

[15] Yale School of Public Health,undefined

来源：

AIDS and Behavior | 2022年 / 26卷

关键词：

Alcohol consumption; Phosphatidylethanolamine; HIV infection;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

The timeline followback (TLFB) takes more resources to collect than the Alcohol Use Disorder Identification Test (AUDIT-C). We assessed agreement of TLFB and AUDIT-C with the biomarker phosphatidylethanol (PEth) and compared changes in TLFB and PEth among persons with HIV (PWH) using secondary data from randomized trials. We calculated operating characteristics and agreement between TLFB (> 1 and > 2 average drinks/day), AUDIT-C ≥ 4 and PEth ≥ 20 among 275 men with HIV. Median age was 57 years, 80% were African-American; and 17% white. Sixty-eight percent had PEth ≥ 20, 46% reported > 2 average drinks/day on TLFB, 61% reported > 1 average drinks/day on TLFB, and 72% had an AUDIT-C ≥ 4. Relative to PEth, sensitivity for AUDIT-C ≥ 4 was 84% (kappa = 0.36), and for TLFB > 1 average drink/day was 76% (kappa = 0.44). Change in alcohol use appeared greater using TLFB measures than PEth. Strategies to robustly assess alcohol use in PWH may require both self-report and biomarkers.

引用

页码：786 / 794

页数：8

共 50 条

[1] Change in Alcohol Use Based on Self-Report and a Quantitative Biomarker, Phosphatidylethanol, in People With HIV
McGinnis, Kathleen A.
Tate, Janet P.
Bryant, Kendall J.
Justice, Amy C.
O'Connor, Patrick G.
Rodriguez-Barradas, Maria C.
Crystal, Stephen
Cutter, Christopher J.
Hansen, Nathan B.
Maisto, Stephen A.
Marconi, Vincent C.
Williams, Emily C.
Cook, Robert L.
Gordon, Adam J.
Gordon, Kirsha S.
Eyawo, Oghenowede
Edelman, E. Jennifer
Fiellin, David A.
AIDS AND BEHAVIOR, 2022, 26 (03) : 786 - 794
[2] Phosphatidylethanol (PEth) as a Biomarker of Alcohol Consumption in HIV-Infected Young Russian Women: Comparison to Self-Report Assessments of Alcohol Use
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[3] Phosphatidylethanol (PEth) as a Biomarker of Alcohol Consumption in HIV-Infected Young Russian Women: Comparison to Self-Report Assessments of Alcohol Use
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