Metallomicellar Systems Based on the Complexes of 1-Hexadecyl-4-aza-1-azoniabicyclo[2.2.2]octane Bromide with Transition Metal Nitrates

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作者
M. R. Ibatullina
E. P. Zhil’tsova
S. S. Lukashenko
A. D. Voloshina
A. S. Sapunova
O. A. Lenina
I. R. Nizameev
M. P. Kutyreva
L. Ya. Zakharova
机构
[1] Russian Academy of Sciences,A.E. Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center
[2] Tupolev Kazan National Research Technological University,Butlerov Chemical Institute
[3] Kazan (Volga Region) Federal University,undefined
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monoquaternized 1,4-diazabicyclo[2.2.2]octane; complexes; surfactants; aggregation; biological activity;
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摘要
Potentiometry, fluorimetry, dynamic light scattering, and transmission electron microscopy were used to study the aggregation properties of the complexes 1-hexadecyl-4-aza-1-azoniabicyclo[2.2.2]octane bromide with transition metal nitrates [Cu(II), Ni(II), Co(II), and La(III)]. The critical micelle concentrations, aggregation numbers, the degree of counterion binding to micelles, the size of aggregates, and electrokinetic potentials were determined. The complexes exhibited a high antimicrobial activity, and some of them proved to be more potent than the reference drugs.
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页码:2359 / 2367
页数:8
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