Phase II trial of carboplatin and pemetrexed as first-line chemotherapy for non-squamous non-small cell lung cancer, and correlation between the efficacy/toxicity and genetic polymorphisms associated with pemetrexed metabolism: Hokkaido Lung Cancer Clinical Study Group Trial (HOT) 0902

被引：0
|
作者：
Kenya Kanazawa
Hiroshi Yokouchi
Xintao Wang
Takashi Ishida
Yuka Fujita
Satoru Fujiuchi
Toshiyuki Harada
Masao Harada
Kei Takamura
Satoshi Oizumi
Ichiro Kinoshita
Yutaka Katsuura
Osamu Honjo
Tetsuya Kojima
Hirotoshi Dosaka-Akita
Hiroshi Isobe
Mitsuru Munakata
Masaharu Nishimura
机构：
[1] Fukushima Medical University School of Medicine,Department of Pulmonary Medicine
[2] Fukushima Medical University Hospital,Clinical Oncology Center
[3] National Hospital Organization Asahikawa Medical Center,Department of Respiratory Medicine
[4] Japan Community Health Care Organization Hokkaido Hospital,Center for Respiratory Disease
[5] National Hospital Organization Hokkaido Cancer Center,Department of Respiratory Medicine
[6] Hokkaido P. W. F. A. C. Obihiro-Kosei General Hospital,First Department of Medicine
[7] Hokkaido University School of Medicine,First Department of Medicine
[8] Hokkaido University Graduate School of Medicine,Department of Medical Oncology
[9] Saiseikai Fukushima General Hospital,Department of Pulmonary Medicine
[10] Hokkaido P. W. F. A. C. Sapporo-Kosei General Hospital,Department of Respiratory Medicine
[11] KKR Sapporo Medical Center,Department of Medical Oncology and Respiratory Medicine
来源：
Cancer Chemotherapy and Pharmacology | 2014年 / 74卷
关键词：
Non-squamous non-small cell lung cancer; Carboplatin; Pemetrexed; Genetic polymorphisms; Methylenetetrahydrofolate reductase (MTHFR); Thymidylate synthase (TS);
D O I：
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页码：1149 / 1157
页数：8
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