Genome-wide dissection of the quorum sensing signalling pathway in Trypanosoma brucei

被引：0

作者：

Binny M. Mony

Paula MacGregor

Alasdair Ivens

Federico Rojas

Andrew Cowton

Julie Young

David Horn

Keith Matthews

机构：

[1] Centre for Immunity,

[2] Infection and Evolution,undefined

[3] Institute for Immunology and Infection Research,undefined

[4] School of Biological Sciences,undefined

[5] University of Edinburgh,undefined

[6] Edinburgh EH9 3JT,undefined

[7] UK,undefined

[8] Biological Chemistry & Drug Discovery,undefined

[9] College of Life Sciences,undefined

[10] University of Dundee,undefined

[11] Dow Street,undefined

[12] Dundee DD1 5EH,undefined

[13] UK,undefined

来源：

Nature | 2014年 / 505卷

关键词：

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Here a genome-wide RNAi library screen is used to identify components of the signalling pathway that allow transformation of Trypanosoma brucei spp., the protozoan parasite responsible for important human and livestock diseases in sub-Saharan Africa, from proliferative slender forms to arrested stumpy forms which are transmitted to the tsetse fly vector.

引用

页码：681 / 685

页数：4

共 50 条

[1] Genome-wide dissection of the quorum sensing signalling pathway in Trypanosoma brucei
Mony, Binny M.
MacGregor, Paula
Ivens, Alasdair
Rojas, Federico
Cowton, Andrew
Young, Julie
Horn, David
Matthews, Keith
NATURE, 2014, 505 (7485) : 681 - +
[2] Genome-wide computational identification of functional RNA elements in Trypanosoma brucei
Mao, Yuan
Najafabadi, Hamed Shateri
Salavati, Reza
BMC GENOMICS, 2009, 10
[3] Genome-wide computational identification of functional RNA elements in Trypanosoma brucei
Yuan Mao
Hamed Shateri Najafabadi
Reza Salavati
BMC Genomics, 10
[4] Genome-wide subcellular protein map for the flagellate parasite Trypanosoma brucei
Billington, Karen
Halliday, Clare
Madden, Ross
Dyer, Philip
Barker, Amy Rachel
Moreira-Leite, Flavia Fernandes
Carrington, Mark
Vaughan, Sue
Hertz-Fowler, Christiane
Dean, Samuel
Sunter, Jack Daniel
Wheeler, Richard John
Gull, Keith
NATURE MICROBIOLOGY, 2023, 8 (03) : 533 - 547
[5] Genome-wide subcellular protein map for the flagellate parasite Trypanosoma brucei
Karen Billington
Clare Halliday
Ross Madden
Philip Dyer
Amy Rachel Barker
Flávia Fernandes Moreira-Leite
Mark Carrington
Sue Vaughan
Christiane Hertz-Fowler
Samuel Dean
Jack Daniel Sunter
Richard John Wheeler
Keith Gull
Nature Microbiology, 2023, 8 : 533 - 547
[6] De Novo Genome Assembly Shows Genome Wide Similarity between Trypanosoma brucei brucei and Trypanosoma brucei rhodesiense
Sistrom, Mark
Evans, Benjamin
Benoit, Joshua
Balmer, Oliver
Aksoy, Serap
Caccone, Adalgisa
PLOS ONE, 2016, 11 (02):
[7] Genome-wide function of MCM-BP in Trypanosoma brucei DNA replication and transcription
Kim, Hee-Sook
NUCLEIC ACIDS RESEARCH, 2019, 47 (02) : 634 - 647
[8] Mitochondrial membrane potential-based genome-wide RNAi screen of Trypanosoma brucei
Zdeněk Verner
Zdeněk Paris
Julius Lukeš
Parasitology Research, 2010, 106 : 1241 - 1244
[9] Mitochondrial membrane potential-based genome-wide RNAi screen of Trypanosoma brucei
Verner, Zdenek
Paris, Zdenek
Lukes, Julius
PARASITOLOGY RESEARCH, 2010, 106 (05) : 1241 - 1244
[10] A quorum sensing-independent path to stumpy development in Trypanosoma brucei
Zimmermann, Henriette
Subota, Ines
Batram, Christopher
Kramer, Susanne
Janzen, Christian J.
Jones, Nicola G.
Engstler, Markus
PLOS PATHOGENS, 2017, 13 (04)

← 1 2 3 4 5 →