Irreversible Electroporation in Locally Advanced Pancreatic Adenocarcinoma: Aiming to Improve Overall Survival

被引：0
|
作者：
Diego Tristán Enjuto
Norberto Herrera Merino
José María Abadal Villandrade
Esther Gálvez González
Rosa Llorente Lázaro
Patricia Díaz Peña
María Jesús Álvarez Pérez
Marta Pérez González
机构：
[1] Hospital Universitario Severo Ochoa,General and Digestive Surgery Department
[2] Hospital Universitario Severo Ochoa,Interventional Radiology Department
来源：
Journal of Gastrointestinal Cancer | 2020年 / 51卷
关键词：
Locally advanced pancreatic cancer; Ablation techniques; Irreversible electroporation;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Irreversible electroporation (IRE) is a non-thermic ablation therapy which has been proposed for locally advanced pancreatic adenocarcinoma (LAPC) as well as for the local control of other types of tumors (kidney or liver). Its use has been extended in the last few years worldwide. Its advantage over other ablation techniques is that it only affects the lipids bilayer of the cell membrane avoiding vascular damage. Safety and viability have been demonstrated in recent studies. Overall survival seems (OS) to improve when it is combined with chemotherapy compared to chemotherapy with or without radiotherapy. Clinical trials should confirm these encouraging data.
引用
收藏
页码：1084 / 1087
页数：3
相关论文
共 50 条
  • [1] Irreversible Electroporation in Locally Advanced Pancreatic Adenocarcinoma: Aiming to Improve Overall Survival
    Tristan Enjuto, Diego
    Herrera Merino, Norberto
    Abadal Villandrade, Jose Maria
    Galvez Gonzalez, Esther
    Llorente Lazaro, Rosa
    Diaz Pena, Patricia
    Alvarez Perez, Maria Jesus
    Perez Gonzalez, Marta
    JOURNAL OF GASTROINTESTINAL CANCER, 2020, 51 (03) : 1084 - 1087
  • [2] Irreversible Electroporation in Locally Advanced Pancreatic Cancer: Potential Improved Overall Survival
    Martin, Robert C. G., II
    McFarland, Kelli
    Ellis, Susan
    Velanovich, Vic
    ANNALS OF SURGICAL ONCOLOGY, 2013, 20 : S443 - S449
  • [3] Irreversible Electroporation in Locally Advanced Pancreatic Cancer: Potential Improved Overall Survival
    Robert C. G. Martin
    Kelli McFarland
    Susan Ellis
    Vic Velanovich
    Annals of Surgical Oncology, 2013, 20 : 443 - 449
  • [4] Irreversible Electroporation of Locally Advanced Pancreatic Head Adenocarcinoma
    Martin, Robert C. G.
    JOURNAL OF GASTROINTESTINAL SURGERY, 2013, 17 (10) : 1850 - 1856
  • [5] Irreversible Electroporation of Locally Advanced Pancreatic Head Adenocarcinoma
    Robert C. G. Martin
    Journal of Gastrointestinal Surgery, 2013, 17 : 1850 - 1856
  • [6] Image Guided Irreversible Electroporation in Locally Advanced Pancreatic Cancer: Improved Overall Survival
    Martin, R. C.
    Hayes, D.
    Goodwin, W.
    McFarlin, K.
    Prasad, M.
    Velanovich, V.
    ANNALS OF SURGICAL ONCOLOGY, 2012, 19 : S11 - S11
  • [7] Irreversible electroporation of locally advanced pancreatic neck/body adenocarcinoma
    Martin, Robert C. G., II
    JOURNAL OF GASTROINTESTINAL ONCOLOGY, 2015, 6 (03) : 329 - 335
  • [8] An update on the role of irreversible electroporation in locally advanced pancreatic adenocarcinoma
    Martin, Robert C. G., II
    HPB, 2016, 18 (10) : 791 - 792
  • [9] Irreversible Electroporation Therapy in the Management of Locally Advanced Pancreatic Adenocarcinoma
    Martin, Robert C. G., II
    McFarland, Kelli
    Ellis, Susan
    Velanovich, Vic
    JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS, 2012, 215 (03) : 361 - 369
  • [10] Percutaneous irreversible electroporation with systemic treatment for locally advanced pancreatic adenocarcinoma
    Leen, Edward
    Picard, John
    Stebbing, Justin
    Abel, Mark
    Dhillon, Tony
    Wasan, Harpreet
    JOURNAL OF GASTROINTESTINAL ONCOLOGY, 2018, 9 (02) : 275 - 281
12345