Teriparatide Therapy for Denosumab-Induced Osteonecrosis of the Jaw in a Male Osteoporotic Patient

被引:0
|
作者
Audrey Neuprez
E. Rompen
J. M. Crielaard
Jean-Yves Reginster
机构
[1] University of Liège,Belgium and Bone and Cartilage Metabolism Unit, Department of Public Health, Epidemiology and Health Economics
[2] CHU,Stomatology Department
[3] CHU,Motricity Sciences Department
[4] CHU,undefined
来源
Calcified Tissue International | 2014年 / 95卷
关键词
Denosumab; Osteonecrosis; Teriparatide; Treatment;
D O I
暂无
中图分类号
学科分类号
摘要
We report the first case of teriparatide adjuvant role in the management of a denosumab-induced osteonecrosis of the jaw in a male subject with idiopathic osteoporosis. Clinical benefits and CT healing were obtained within 2 months of teriparatide initiation and denosumab withdrawal. Increase in bone turnover previously described, when denosumab treatment is removed, might have a synergistic effect to the stimulating effect of teriparatide on bone remodeling to promptly heal osteonecrosis of the jaw.
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页码:94 / 96
页数:2
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