Early changes in gene expression and inflammatory proteins in systemic juvenile idiopathic arthritis patients on canakinumab therapy

被引：0
|
作者：
Arndt H. Brachat
Alexei A. Grom
Nico Wulffraat
Hermine I. Brunner
Pierre Quartier
Riva Brik
Liza McCann
Huri Ozdogan
Lidia Rutkowska-Sak
Rayfel Schneider
Valeria Gerloni
Liora Harel
Maria Terreri
Kristin Houghton
Rik Joos
Daniel Kingsbury
Jorge M. Lopez-Benitez
Stephan Bek
Martin Schumacher
Marie-Anne Valentin
Hermann Gram
Ken Abrams
Alberto Martini
Daniel J. Lovell
Nanguneri R. Nirmala
Nicolino Ruperto
机构：
[1] Novartis Institutes for Biomedical Research,
[2] Cincinnati Children’s Hospital Medical Center,undefined
[3] PRCSG,undefined
[4] Wilhelmina Kinderziekenhuis,undefined
[5] Department of Pediatric Immunology and Rheumatology,undefined
[6] Université Paris-Descartes,undefined
[7] IMAGINE Institute,undefined
[8] Hôpital Necker-Enfants Malades. Centre de référence national pour les Arthrites Juveniles,undefined
[9] Unité d’Immunologie,undefined
[10] Hématologie et Rhumatologie Pediatrique,undefined
[11] Rambam Medical Center,undefined
[12] Department of Pediatrics B,undefined
[13] Alder Hey Children’s NHS Foundation Trust,undefined
[14] Cerrahpasa Tip Fakultesi,undefined
[15] Ic Hastaliklari ABD,undefined
[16] Romatoloji BD,undefined
[17] Institute of Rheumatology,undefined
[18] Paediatric Clinic,undefined
[19] Hospital for Sick Children,undefined
[20] Division of Rheumatology,undefined
[21] Istituto Gaetano Pini,undefined
[22] Divisione di Reumatologia,undefined
[23] Schneider Childrens Medical Center,undefined
[24] Pediatric Rheumatology Unit,undefined
[25] Universidade Federal de São Paulo,undefined
[26] Pediatrics,undefined
[27] British Columbia Children’s Hospital,undefined
[28] Universitair Ziekenhuis Gent,undefined
[29] Centrum Voor Kinderreumatologie,undefined
[30] Randall Children’s Hospital at Legacy Emanuel,undefined
[31] Floating Hospital for Children,undefined
[32] Rheumatology NEMC 286,undefined
[33] Novartis Pharmaceuticals Corporation,undefined
[34] University of Genova and Istituto Giannina Gaslini,undefined
[35] Pediatria II-PRINTO,undefined
[36] Novartis Institutes for Biomedical Research,undefined
[37] Istituto Giannina Gaslini,undefined
[38] Pediatria II-PRINTO,undefined
来源：
Arthritis Research & Therapy | / 19卷
关键词：
Biomarkers; Canakinumab; Gene expression; Interleukin-1β; Juvenile idiopathic arthritis; SJIA;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [1] Early changes in gene expression and inflammatory proteins in systemic juvenile idiopathic arthritis patients on canakinumab therapy
    Brachat, Arndt H.
    Grom, Alexei A.
    Wulffraat, Nico
    Brunner, Hermine I.
    Quartier, Pierre
    Brik, Riva
    McCann, Liza
    Ozdogan, Huri
    Rutkowska-Sak, Lidia
    Schneider, Rayfel
    Gerloni, Valeria
    Harel, Liora
    Terreri, Maria
    Houghton, Kristin
    Joos, Rik
    Kingsbury, Daniel
    Lopez-Benitez, Jorge M.
    Bek, Stephan
    Schumacher, Martin
    Valentin, Marie-Anne
    Gram, Hermann
    Abrams, Ken
    Martini, Alberto
    Lovell, Daniel J.
    Nirmala, Nanguneri R.
    Ruperto, Nicolino
    ARTHRITIS RESEARCH & THERAPY, 2017, 19
  • [2] CHANGES IN GENE EXPRESSION AND INFLAMMATORY PROTEINS IN SYSTEMIC JUVENILE IDIOPATHIC ARTHRITIS PATIENTS ON CANAKINUMAB THERAPY
    Brachat, A.
    Grom, A.
    Wulffraat, N.
    Brunner, H.
    Quartier, P.
    Brik, R.
    McCann, L.
    Ozdogan, H.
    Rutkowska-Sak, L.
    Schneider, R.
    Gerloni, V.
    Harel, L.
    Terreri, M.
    Houghton, K.
    Joos, R.
    Kingsbury, D.
    Lopez-Benitez, J.
    Bek, S.
    Schumacher, M.
    Valentin, M.
    Gram, H.
    Abrams, K.
    Martini, A.
    Ruperto, N.
    Lovell, D.
    Nirmala, N.
    ANNALS OF THE RHEUMATIC DISEASES, 2014, 73 : 62 - 62
  • [3] Characterization Of Changes In Gene Expression and Inflammatory Proteins In Systemic Juvenile Idiopathic Arthritis Patients On Canakinumab Therapy
    Nirmala, Nanguneri. R.
    Wulffraat, Nico
    Brunner, Hermine
    Quartier, Pierre
    Brik, Riva
    McCann, Liza
    Ozdogan, Huri
    Rutkowska-Sak, Lidia
    Schneider, Rayfel
    Gerloni, Valeria
    Harel, Liora
    Terreri, Maria
    Houghton, Kristin
    Joos, Rik
    Kingsbury, Daniel
    Lopez-Benitez, Jorge M.
    Brachat, Arndt
    Bek, Stephan
    Schumacher, Martin
    Valentin, Marie-Anne
    Gram, Hermann
    Abrams, Ken
    Martini, Alberto
    Ruperto, Nicolino
    Lovell, Daniel J.
    ARTHRITIS AND RHEUMATISM, 2013, 65 : S716 - S716
  • [4] Analysis of Biomarkers in Systemic Juvenile Idiopathic Arthritis Patients On Canakinumab Therapy.
    Wulffraat, Nico
    Brunner, Hermine I.
    Ruperto, Nicolino
    Quartier, Pierre
    Brik, Riva
    McCann, Liza
    Ozdogan, Huri
    Rutkowska-Sak, Lidia
    Schneider, Rayfel
    Gerloni, Valeria
    Harel, Liora
    Hilario, Maria
    Houghton, Kristin
    Joos, Rik
    Kingsbury, Daniel
    Brachat, Arndt
    Bek, Stephan
    Schumacher, Martin
    Valentin, Marie-Anne
    Nirmala, N. R.
    Gram, Hermann
    Abrams, Ken
    Martini, Alberto
    Lovell, D. J.
    ARTHRITIS AND RHEUMATISM, 2012, 64 (10): : S328 - S328
  • [5] Pharmacokinetics and Pharmacodynamics of Canakinumab in Patients With Systemic Juvenile Idiopathic Arthritis
    Sun, Haiying
    Van, Linh M.
    Floch, David
    Jiang, Xuemin
    Klein, Ulf R.
    Abrams, Ken
    Sunkara, Gangadhar
    JOURNAL OF CLINICAL PHARMACOLOGY, 2016, 56 (12): : 1516 - 1527
  • [6] Tapering canakinumab in systemic juvenile idiopathic arthritis
    Thorley, Jennifer
    LANCET RHEUMATOLOGY, 2020, 2 (10): : E593 - E593
  • [7] Canakinumab (Ilaris) for Systemic Juvenile Idiopathic Arthritis
    不详
    MEDICAL LETTER ON DRUGS AND THERAPEUTICS, 2013, 55 (1423): : 65 - 66
  • [8] Canakinumab for the treatment of systemic juvenile idiopathic arthritis
    Grom, Alexei A.
    EXPERT REVIEW OF CLINICAL IMMUNOLOGY, 2014, 10 (11) : 1427 - 1435
  • [9] PReS-FINAL-2156: Analysis of gene expression and inflammation biomarkers in systemic juvenile idiopathic arthritis (SJIA) patients on canakinumab therapy
    N Nirmala
    N Wulffraat
    H Brunner
    P Quartier
    R Brik
    L Mccann
    H Ozdogan
    L Rutkowska-Sak
    R Schneider
    V Gerloni
    L Harel
    M Terreri
    K Houghton
    R Joos
    D Kingsbury
    J Lopez-Benitez
    S Radominski
    A Brachat
    S Bek
    M Schumacher
    M Valentin
    H Gram
    K Abrams
    A Martini
    N Ruperto
    D Lovell
    Pediatric Rheumatology, 11 (Suppl 2)
  • [10] MAINTENANCE OF EFFICACY BY CANAKINUMAB TREATMENT IN SYSTEMIC JUVENILE IDIOPATHIC ARTHRITIS PATIENTS
    Wulffraat, N. M.
    Ruperto, N.
    Brunner, H. I.
    Oliveira, S.
    Uziel, Y.
    Nistala, K.
    Cimaz, R.
    Ferrandiz, M. A.
    Flato, B.
    Gamir, M. L.
    Kone-Paut, I.
    Gaillez, C.
    Lheritier, K.
    Abrams, K.
    Martini, A.
    Lovell, D. J.
    ANNALS OF THE RHEUMATIC DISEASES, 2014, 73 : 130 - 130
12345