Pulmonary Hypertension in an Infant Treated with Ibuprofen

被引：0
|
作者：
Arvind Sehgal
Prasanna S. N. Kumarshingri
机构：
[1] Monash University,Monash Newborn, Monash Children’s
[2] Monash University,Monash Newborn, Monash Children’s
来源：
The Indian Journal of Pediatrics | 2013年 / 80卷
关键词：
Ibuprofen; Patent ductus arteriosus; Pulmonary hypertension;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Presence of symptomatic patent ductus arteriosus is common in small preterm infants and ibuprofen is commonly used for its medical closure. While efficacy is comparable to indomethacin, there are few case reports of severe hypoxemia and pulmonary hypertension following prophylactic ibuprofen administration. Cumulative dose effects and chemical composition may be important considerations. Possible mechanisms of occurrence of this complication in a preterm infant are discussed.
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页码：697 / 699
页数：2
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