Integrated chromatin accessibility and DNA methylation analysis to reveal the critical epigenetic modification and regulatory mechanism in gonadal differentiation of the sequentially hermaphroditic fish, Monopterus albus

被引：0

作者：

Qiaomu Hu

Zitong Lian

Xueping Xia

Haifeng Tian

Zhong Li

机构：

[1] Yangtze River Fisheries Research Institute,

[2] Chinese Academy of Fishery Sciences,undefined

来源：

Biology of Sex Differences | / 13卷

关键词：

Sex reversal; DNA methylation; Chromatin accessibility; Epigenetic modification;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

DNA methylation modification plays a more crucial role than chromatin accessibility in gonad development.DNA methylation in the transcription start site plays a key role in gonad development.DNA methylation of the plastin-2 promoter inhibited gene expression.Plastin-2 is positively regulated by dmrt1 while negatively regulated by foxl2.

引用

共 4 条

[1] Integrated chromatin accessibility and DNA methylation analysis to reveal the critical epigenetic modification and regulatory mechanism in gonadal differentiation of the sequentially hermaphroditic fish, Monopterus albus
Hu, Qiaomu
Lian, Zitong
Xia, Xueping
Tian, Haifeng
Li, Zhong
BIOLOGY OF SEX DIFFERENCES, 2022, 13 (01)
[2] DNA methylation modification is associated with gonadal differentiation in Monopterus albus
Wang, Xin
Lai, Fengling
Xiong, Jun
Zhu, Wang
Yuan, Bifeng
Cheng, Hanhua
Zhou, Rongjia
CELL AND BIOSCIENCE, 2020, 10 (01):
[3] DNA methylation modification is associated with gonadal differentiation in Monopterus albus
Xin Wang
Fengling Lai
Jun Xiong
Wang Zhu
Bifeng Yuan
Hanhua Cheng
Rongjia Zhou
Cell & Bioscience, 10
[4] Analysis of Chromatin Accessibility and DNA Methylation to Reveal the Functions of Epigenetic Modifications in Cyprinus carpio Gonads
Hou, Mingxi
Wang, Qi
Zhao, Ran
Cao, Yiming
Zhang, Jin
Sun, Xiaoqing
Yu, Shuangting
Wang, Kaikuo
Chen, Yingjie
Zhang, Yan
Li, Jiongtang
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2024, 25 (01)

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