Attenuation of WNT signaling by DKK-1 and -2 regulates BMP2-induced osteoblast differentiation and expression of OPG, RANKL and M-CSF

被引：0
|
作者：
Ken-ichi Fujita
Siegfried Janz
机构：
[1] National Institutes of Health,Laboratory of Genetics, Center for Cancer Research, National Cancer Institute
[2] Roy J. and Lucille A. Carver College of Medicine,Department of Pathology
[3] University of Iowa,undefined
来源：
Molecular Cancer | / 6卷
关键词：
Green Fluorescent Protein; Osteoblast Differentiation; C2C12 Cell; Bone Morphogenic Protein; BMP2 Signaling;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [1] Attenuation of WNT signaling by DKK-1 and -2 regulates BMP2-induced osteoblast differentiation and expression of OPG, RANKL and M-CSF
    Fujita, Ken-ichi
    Janz, Siegfried
    MOLECULAR CANCER, 2007, 6 (1)
  • [2] Regulation of Notch signaling genes during BMP2-induced differentiation of osteoblast precursor cells
    de Jong, DS
    Steegenga, WT
    Hendriks, JMA
    van Zoelen, EJJ
    Olijve, W
    Dechering, KJ
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2004, 320 (01) : 100 - 107
  • [3] PDZRN3 Negatively Regulates BMP-2-induced Osteoblast Differentiation through Inhibition of Wnt Signaling
    Honda, Takeshi
    Yamamoto, Hisato
    Ishii, Aiko
    Inui, Makoto
    MOLECULAR BIOLOGY OF THE CELL, 2010, 21 (18) : 3269 - 3277
  • [4] Tunicamycin negatively regulates BMP2-induced osteoblast differentiation through CREBH expression in MC3T3E1 cells
    Jang, Won Gu
    Kim, Eun Jung
    Koh, Jeong-Tae
    BMB REPORTS, 2011, 44 (11) : 735 - 740
  • [5] Effects of intermedin on proliferation, apoptosis and the expression of OPG/RANKL/M-CSF in the MC3T3-E1 osteoblast cell line
    Ren, Hongfei
    Ren, Hongyu
    Li, Xue
    Yui, Dongdong
    Mu, Shuai
    Chen, Zhiguang
    Fu, Qin
    MOLECULAR MEDICINE REPORTS, 2015, 12 (05) : 6711 - 6717
  • [6] HtrA1 is upregulated during RANKL-induced osteoclastogenesis, and negatively regulates osteoblast differentiation and BMP2-induced Smad1/5/8, ERK and p38 phosphorylation
    Wu, Xinghuo
    Chim, Shek Man
    Kuek, Vincent
    Lim, Bay Sie
    Chow, Siu To
    Zhao, Jinmin
    Yang, Shuhua
    Rosen, Vicki
    Tickner, Jennifer
    Xu, Jiake
    FEBS LETTERS, 2014, 588 (01) : 143 - 150
  • [7] Secreted frizzled related protein 1 regulates Wnt signaling for BMP2 induced chondrocyte differentiation
    Gaur, Tripti
    Rich, Lillian
    Lengner, Christopher J.
    Hussain, Sadiq
    Trevant, Rune
    Ayers, David
    Stein, Janet L.
    Bodine, Peter V. N.
    Komm, Barry S.
    Stein, Gary S.
    Lian, Jane B.
    JOURNAL OF CELLULAR PHYSIOLOGY, 2006, 208 (01) : 87 - 96
  • [8] The Orphan Nuclear Receptor Estrogen Receptor-related Receptor γ Negatively Regulates BMP2-induced Osteoblast Differentiation and Bone Formation
    Jeong, Byung-Chul
    Lee, Yong-Soo
    Park, Yun-Yong
    Bae, In-Ho
    Kim, Don-Kyu
    Koo, Seung-Hoi
    Choi, Hong-Ran
    Kim, Sun-Hun
    Franceschi, Renny T.
    Koh, Jeong-Tae
    Choi, Hueng-Sik
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2009, 284 (21) : 14211 - 14218
  • [9] COMP-Ang1, a chimeric form of Angiopoietin 1, enhances BMP2-induced osteoblast differentiation and bone formation
    Jeong, Byung-Chul
    Kim, Hyun-Joo
    Bae, In-Ho
    Lee, Kkot-Nim
    Lee, Kwang-Youl
    Oh, Won-Mann
    Kim, Sun-Hun
    Kang, In-Chol
    Lee, Shee-Eun
    Koh, Gou-Young
    Kim, Kyung-Keun
    Koh, Jeong-Tae
    BONE, 2010, 46 (02) : 479 - 486
  • [10] Nrf2 Mitigates RANKL and M-CSF Induced Osteoclast Differentiation via ROS-Dependent Mechanisms
    Yang, Yang
    Liu, Zhiyuan
    Wu, Jinzhi
    Bao, Simeng
    Wang, Yanshuai
    Li, Jiliang
    Song, Tao
    Sun, Yongxin
    Pi, Jingbo
    ANTIOXIDANTS, 2023, 12 (12)
12345