Novel acyclic nucleoside analogues as inhibitors of HIV-1 RT

被引：0
|
作者：
Anuradha Singh
Madhu Yadav
Dipti Yadav
Garima Kumari
Ramendra K Singh
机构：
[1] University of Allahabad,Nucleic Acids Research Laboratory, Department of Chemistry
来源：
BMC Infectious Diseases | / 12卷 / Suppl 1期
关键词：
Nucleoside; Uracil; Nucleoside Analog; Nucleoside Reverse Transcriptase Inhibitor; Alternate Substrate;
D O I：
10.1186/1471-2334-12-S1-P43
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [1] MECHANISMS OF RESISTANCE OF HIV-1 RT TO NUCLEOSIDE AND NONNUCLEOSIDE INHIBITORS
    BOYER, PL
    TANTILLO, C
    DING, JP
    FERRIS, AL
    CLARK, P
    ARNOLD, E
    HUGHES, SH
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1995, 209 : 150 - MEDI
  • [2] Computational strategies in discovering novel non-nucleoside inhibitors of HIV-1 RT
    Barreca, ML
    Rao, A
    De Luca, L
    Zappalà, L
    Monforte, AM
    Maga, G
    Pannecouque, C
    Balzarini, J
    De Clercq, E
    Chimirri, A
    Monforte, P
    JOURNAL OF MEDICINAL CHEMISTRY, 2005, 48 (09) : 3433 - 3437
  • [3] Structural determinants and molecular mechanisms for the resistance of HIV-1 RT to nucleoside analogues
    Deval, J
    Courcambeck, J
    Selmi, B
    Boretto, J
    Canard, B
    CURRENT DRUG METABOLISM, 2004, 5 (04) : 305 - 316
  • [4] Design and synthesis of novel distamycin-modified nucleoside analogues as HIV-1 reverse transcriptase inhibitors
    Li, Chao
    Ma, Chunying
    Zhang, Jin
    Qian, Ning
    Ding, Jingjing
    Qiao, Renzhong
    Zhao, Yufen
    ANTIVIRAL RESEARCH, 2014, 102 : 54 - 60
  • [5] Acyclic nucleoside analogues as novel inhibitors of human mitochondrial thymidine kinase
    Hernández, AI
    Balzarini, J
    Karlsson, A
    Camarasa, MJ
    Pérez-Pérez, MJ
    JOURNAL OF MEDICINAL CHEMISTRY, 2002, 45 (19) : 4254 - 4263
  • [6] Fragment screening identifies novel HIV-1 RT inhibitors
    Sarah Crunkhorn
    Nature Reviews Drug Discovery, 2015, 14 (7) : 460 - 460
  • [7] SPECIFIC HIV-1 INHIBITORS TARGETED AT THE HIV-1 RT
    DECLERCQ, E
    JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES AND HUMAN RETROVIROLOGY, 1993, 6 (06): : 673 - 673
  • [8] Enzymatic synthesis of acyclic nucleoside thiophosphonate diphosphates: Effect of the α-phosphorus configuration on HIV-1 RT activity
    Priet, Stephane
    Roux, Loic
    Saez-Ayala, Magali
    Ferron, Francois
    Canard, Bruno
    Alvarez, Karine
    ANTIVIRAL RESEARCH, 2015, 117 : 122 - 131
  • [9] Primer unblocking by HIV-1 reverse transcriptase and resistance to nucleoside RT inhibitors (NRTIs)
    Goldschmidt, V
    Marquet, R
    INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY, 2004, 36 (09): : 1687 - 1705
  • [10] Synthesis of nucleoside analogs for inhibition of HIV-1 RT
    Mueller-Mabry, Brittany
    Ledezma, Carlos
    Kolpashchikov, Dmitry
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2019, 257
12345