Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection

被引：0
|
作者：
Shawn D Blackburn
Haina Shin
W Nicholas Haining
Tao Zou
Creg J Workman
Antonio Polley
Michael R Betts
Gordon J Freeman
Dario A A Vignali
E John Wherry
机构：
[1] Immunology Program and Wistar Vaccine Center,Department of Hematology/Oncology
[2] The Wistar Institute,Department of Microbiology
[3] Children's Hospital,Department of Immunology
[4] Pediatric Oncology,undefined
[5] Dana Farber Cancer Institute,undefined
[6] Medical Oncology,undefined
[7] Dana Farber Cancer Institute,undefined
[8] University of Pennsylvania,undefined
[9] St. Jude Children's Research Hospital,undefined
来源：
Nature Immunology | 2009年 / 10卷
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摘要：
Chronic infection can lead to T cell exhaustion. Wherry and colleagues demonstrate that a hierarchy of inhibitory receptors coregulate CD8+ T cell exhaustion during chronic viral infection.
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页码：29 / 37
页数：8
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