Synthesis of 2-Aryl-2,3-Dihydroquinazolin-4(1H)-One Derivatives Using Lactic Acid as a Green, Natural and Inexpensive Catalyst in Water

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作者
Tayebeh Jazinizadeh
Malek Taher Maghsoodlou
Reza Heydari
机构
[1] University of Sistan and Baluchestan,Department of Chemistry, Faculty of Science
关键词
Green chemistry; Lactic acid; 2-Aminobenzamide; Aromatic aldehydes;
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摘要
In this work, we used lactic acid as a green and inexpensive catalyst for the synthesis of 2,3-dihydro-2-phenylquinazolin-4(1H)-ones via the cyclocondensation of 2-aminobenzamide and aromatic aldehydes in water. The main advantages of this reaction are green conditions, short reaction times, relatively high yields and simple separation of products.
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页码:1929 / 1933
页数:4
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