Tonsillar p16-Positive Follicular Dendritic Cell Sarcoma Mimicking HPV-Related Oropharyngeal Squamous Cell Carcinoma: A Case Report and Review of Reported Cases

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作者
Bailey Hutchison
Sam Sadigh
Judith A. Ferry
Trisha M. Shattuck
William C. Faquin
机构
[1] Massachusetts General Hospital,Department of Pathology
[2] Atrium Health Carolinas Medical Center,Carolinas Pathology
[3] Massachusetts Eye and Ear Infirmary,undefined
来源
Head and Neck Pathology | 2021年 / 15卷
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摘要
Follicular dendritic cell sarcoma (FDCS) is a rare entity which can share morphologic features with non-keratinizing squamous cell carcinoma. Recent reports suggest that up to half of FDCSs show immunohistochemical positivity for p16 (Zhang et al., in Hum Pathol 66:40–47, 2017), a stain that is conventionally used in the risk stratification of oropharyngeal squamous cell carcinoma (OPSCC). Herein, we report a case of p16-positive FDCS with clinical and histomorphologic overlap with human papilloma virus (HPV)-related OPSCC.
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页码:267 / 274
页数:7
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