EPAC1 boosts thermogenic adipocyte formation

被引：0
|
作者：
Evan D. Rosen
机构：
[1] Beth Israel Deaconess Medical Center,Division of Endocrinology, Diabetes, and Metabolism
来源：
Nature Cell Biology | 2024年 / 26卷 / 1期
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摘要：
β-adrenergic signalling induces thermogenesis in mature brown adipocytes through a well-known cAMP–protein kinase A (PKA) pathway and also promotes the growth and differentiation of new thermogenic adipocytes. A study now demonstrates that β-adrenergic agonists drive this pathway through a PKA-independent mechanism involving cAMP–EPAC1.
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页码：39 / 40
页数：1
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