Synthesis and antibacterial activity of betulonic acid amides with piperazine derivatives

被引：0
|
作者：
K.-T. Chue
M.-S. Chang
L. N. Ten
机构：
[1] Energy Materials Research Center,
[2] Korea Institute of Energy Research,undefined
[3] Biotechnology & Natural Products Lab. Co.,undefined
[4] Ltd.,undefined
来源：
Chemistry of Natural Compounds | 2011年 / 47卷
关键词：
betulonic acid; amides; piperazine derivatives; antibacterial activity;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
New betulonic acid amides with piperazine derivatives were synthesized by the acid-chloride method and characterized using spectral data. It was shown that synthesized compounds 2–7 exhibited varied antibacterial activity. The most active of them was betulonic acid amide of 1-(3,4-dichlorophenyl)piperazine (3) and 1-(4-trifluoromethylphenyl)piperazine (7).
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页码：759 / 763
页数：4
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