The effects of frequency in pallidal deep brain stimulation for primary dystonia

被引：0
|
作者：
A. Kupsch
S. Klaffke
A. A. Kühn
W. Meissner
G. Arnold
G. H. Schneider
K. Maier-Hauff
T. Trottenberg
机构：
[1] Charité,Dept. of Neurology
[2] Campus Virchow,Dept. of Neurosurgery
[3] Humboldt University Berlin,undefined
[4] Charité,undefined
[5] Campus Virchow,undefined
[6] Humboldt University Berlin,undefined
来源：
Journal of Neurology | 2003年 / 250卷
关键词：
dystonia; deep brain stimulation; frequency; stimulation parameter; globus pallidus;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The effect of stimulation frequency for pallidal deep brain stimulation in five patients with either generalized or segmental dystonia was evaluated three to twelve months postoperatively via a randomized, double-blind paradigm. The quality of life and the severity of dystonic symptoms improved by approximately 60% and 43% respectively using a frequency of 130 Hz. Compared with 130 Hz a significant further clinical improvement was observed at frequencies of 180 and 250 Hz, which contrasted with a significant deterioration at lower frequencies (5, 50 Hz) compared to 130 Hz.
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页码：1201 / 1205
页数：4
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