Clay (Montmorillonite K10) Catalysis of the Michael Addition of α,β-Unsaturated Carbonyl Compounds to Indoles: The Beneficial Role of AlcoholsDurch Montmorillonit-K10 katalysierte Michael-Addition von α,β-ungesättigten Carbonylverbindungen an Indole: Zur unterstützenden Wirkung von Alkoholen

被引：0

作者：

Jacques H. Poupaert

Jacques Bukuru

Andrea Gozzo

机构：

[1] Medicinal Chemistry,

[2] School of Pharmacy,undefined

[3] Faculty of Medicine,undefined

[4] UCL,undefined

[5] B-1200 Brussels,undefined

[6] Belgium,undefined

来源：

Monatshefte für Chemie / Chemical Monthly | 1999年 / 130卷 / 7期

关键词：

Keywords. Michael addition; Indole; Montmorillonite K10; Alcohol.;

D O I：

10.1007/PL00010274

中图分类号：

学科分类号：

摘要：

The Michael addition of methylvinylketone to indole can be performed under smooth conditions by running the reaction in the presence of an acidic clay catalyst (K10 Montmorillonite) and an aliphatic alcohol such as ethanol or 2-propanol. Presence of an alcohol along with a polar solvent (nitromethane) in the reaction medium considerably improves the reaction.

引用

页码：929 / 932

页数：3

共 2 条

[1] Clay (Montmorillonite K10) catalysis of the Michael addition of α,β-unsaturated carbonyl compounds to indoles:: The beneficial role of alcohols
Poupaert, JH
Bukuru, J
Gozzo, A
MONATSHEFTE FUR CHEMIE, 1999, 130 (07): : 929 - 932
[2] Ammonium chlorochromate adsorbed on montmorillonite K-10: A new reagent for the oxidation of alcohols to the corresponding carbonyl compounds under non-aqueous conditions [An montmorillonit-K-10 adsorbiertes aminoniumchlorochromat: Ein neues reagens zur oxidation von alkoholen zu carbonylverbindungen unter nichtwäßrigen bedingungen]
Heravi M.M.
Kiakojoori R.
Tabar-Hydar K.
Monatshefte für Chemie / Chemical Monthly, 1999, 130 (4) : 581 - 583

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