Potential use of cidofovir, brincidofovir, and tecovirimat drugs in fighting monkeypox infection: recent trends and advancements

被引:0
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作者
Isha Rani
Hemant Joshi
Ujjawal Sharma
Jagjit Kaur
Shivani Sood
Seema Ramniwas
Abhishek Chauhan
Hadi Sajid Abdulabbas
Hardeep Singh Tuli
机构
[1] Maharishi Markandeshwar College of Medical Sciences and Research (MMCMSR),Department of Biochemistry
[2] Jawaharlal Nehru University,School of Biotechnology
[3] Central University of Punjab,Department of Human Genetics and Molecular Medicine, School of Health Sciences
[4] The University of New South Wales,Graduate School of Biomedical Engineering, Faculty of Engineering
[5] GIOSTAR-USA,University Centre for Research and Development
[6] Global Institute of Stem Cell Therapy and Research,Department of Biology, College of Science
[7] University Institute of Pharmaceutical Sciences,Department of Bio
[8] Chandigarh University,Sciences and Technology
[9] Amity Institute of Environmental Toxicology,undefined
[10] Safety and Management,undefined
[11] Amity University,undefined
[12] University of Babylon,undefined
[13] Maharishi Markandeshwar Engineering College,undefined
[14] Maharishi Markandeshwar (Deemed to Be University),undefined
关键词
Monkeypox; Antiviral medications; Treatment; Infection; Outbreaks; Vaccines;
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摘要
Recent years have witnessed the rise of more recent pandemic outbreaks including COVID-19 and monkeypox. A multinational monkeypox outbreak creates a complex situation that necessitates countermeasures to the existing quo. The first incidence of monkeypox was documented in the 1970s, and further outbreaks led to a public health emergency of international concern. Yet as of right now, neither vaccines nor medicines are certain to treat monkeypox. Even the inability of conducting human clinical trials has prevented thousands of patients from receiving effective disease management. The current state of the disease’s understanding, the treatment options available, financial resources, and lastly international policies to control an epidemic state are the major obstacles to controlling epidemics. The current review focuses on the epidemiology of monkeypox, scientific ideas, and available treatments, including potential monkeypox therapeutic methods. As a result, a thorough understanding of monkeypox literature will facilitate in the development of new therapeutic medications for the prevention and treatment of monkeypox.
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页码:2055 / 2065
页数:10
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