Stretching strongly confined semiflexible polymer chain

By the so-called wormlike chain (WLC) model in polymer physics envisioning an isotropic rod that is continuously flexible, the force-extension relations of semi-flexible polymer chains strongly constrained by various confinements are theoretically investigated, including a slab-like confinement where the polymer chains are sandwiched between two parallel impenetrable walls, and a capped nanochannel confinement with a circular or rectangular cross-section where the chains are bounded in three directions. The Brownian dynamics (BD) simulations based on the generalized bead-rod (GBR) model are performed to verify the theoretical predictions.