Reversible cardiomyopathy caused by administration of interferon α

被引:0
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作者
Aarif Y Khakoo
Marc K Halushka
J Eduardo Rame
E Rene Rodriguez
Edward K Kasper
Daniel P Judge
机构
[1] Division of Cardiology,Department of Pathology
[2] Johns Hopkins University,undefined
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Background A 56-year-old man with normal cardiac function received treatment with interferon α-2b for malignant melanoma. Eight months after the initiation of therapy he developed fatigue and dyspnea on exertion. Two months later, he was admitted to hospital with ORTHOPNEA, worsening dyspnea and cough. Physical examination findings were consistent with congestive heart failure. Laboratory studies were notable for hypothyroidism. Echocardiography revealed severe, global left-ventricular dysfunction.
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页码:53 / 57
页数:4
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