Synthesis and characterization of praseodymium-2-hydroxypropyl-β-cyclodextrin inclusion complex

The inclusion complex of PrCl3-XH2O-2-hidroxypropyl-β-cyclodextrin (Pr-2HPβCD) was prepared to increase the solubility and stability of PrCl3-XH2O. As techniques of characterization, UV-Vis spectroscopy, scanning electron microscopy, X-ray diffraction, infrared spectroscopy, and Raman spectroscopy were used and confirmed the inclusion complex Pr-2HPβCD’s formation. By UV-Vis spectrophotometry, three wavelength regions were established to determine praseodymium in a wide range of concentration in the presence of 2-hidroxypropyl-β-cyclodextrin (2HPβCD). When the Pr-2HPβCD inclusion complex was irradiated with gamma radiation from cobalt-60 at doses between 1 and 500 Gy, the material not changed significantly. However, when the inclusion complex was irradiated between 5000 and 10,000 Gy, small changes occurred, showing that the inclusion complex began to decompose. The Pr-2HPβCD inclusion complex formation contributes to research with new applications of the praseodymium as a therapeutic agent.