Mapping in vivo protein-RNA interactions at single-nucleotide resolution from HITS-CLIP data

被引：0
|
作者：
Chaolin Zhang
Robert B Darnell
机构：
[1] Laboratory of Molecular Neuro-Oncology,
[2] Howard Hughes Medical Institute,undefined
[3] The Rockefeller University,undefined
来源：
Nature Biotechnology | 2011年 / 29卷
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学科分类号：
摘要：
Widely applicable methods for mapping protein-RNA interactions by crosslinking achieve a resolution of ∼30–60 nucleotides. Zhang and Darnell analyze sites of mutation induced by the crosslinking to map binding at single-nucleotide resolution.
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页码：607 / 614
页数：7
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