Protein interaction maps for model organisms

被引:0
|
作者
Albertha J. M. Walhout
Marc Vidal
机构
[1] Dana-Farber Cancer Institute and Department of Genetics Harvard Medical School,
来源
关键词
D O I
暂无
中图分类号
学科分类号
摘要
Until recently, classical genetics and biochemistry were the main techniques used to investigate how organisms develop, reproduce, behave and age. But with the availability of complete genome sequences new approaches are emerging. Complete sets of proteins — 'proteomes' — can be predicted from genome sequences and used to characterize protein functions globally. For example, through the large-scale identification of physical protein–protein interactions, comprehensive protein interaction maps are being generated. And these maps might help us to understand the processes that control the biology of living organisms.
引用
收藏
页码:55 / 63
页数:8
相关论文
共 50 条
  • [1] Protein interaction maps for model organisms
    Walhout, AJM
    Vidal, M
    NATURE REVIEWS MOLECULAR CELL BIOLOGY, 2001, 2 (01) : 55 - 62
  • [2] Protein-protein Interaction Prediction and Assessment from Model Organisms
    Lin, Xiaotong
    Liu, Mei
    Chen, Xue-Wen
    2008 IEEE INTERNATIONAL CONFERENCE ON BIOINFORMATICS AND BIOMEDICINE, PROCEEDINGS, 2008, : 187 - 192
  • [3] On the Planarity of Validated Complexes of Model Organisms in Protein-Protein Interaction Networks
    Cooper, Kathryn
    Cornelius, Nathan
    Gasper, William
    Bhowmick, Sanjukta
    Ali, Hesham
    COMPUTATIONAL SCIENCE - ICCS 2020, PT I, 2020, 12137 : 652 - 666
  • [4] Healthspan pathway maps in model organisms and humans
    Fuellen, G.
    ZEITSCHRIFT FUR GERONTOLOGIE UND GERIATRIE, 2018, 51 : 8 - 8
  • [5] Protein interaction maps on the fly
    Peter Uetz
    Michael J Pankratz
    Nature Biotechnology, 2004, 22 : 43 - 44
  • [6] Protein interaction maps on the fly
    Uetz, P
    Pankratz, MJ
    NATURE BIOTECHNOLOGY, 2004, 22 (01) : 43 - 44
  • [7] Protein interaction maps and biological networks
    Legrain, P.
    MOLECULAR & CELLULAR PROTEOMICS, 2004, 3 (10) : S76 - S76
  • [8] RNAct: Protein-RNA interaction predictions for model organisms with supporting experimental data
    Lang, Benjamin
    Armaos, Alexandros
    Tartaglia, Gian G.
    NUCLEIC ACIDS RESEARCH, 2019, 47 (D1) : D601 - D606
  • [9] NASCENT: An automatic protein interaction network generation tool for non-model organisms
    Banky, Daniel
    Ordoe, Rafael
    Grolmusz, Vince
    BIOINFORMATION, 2009, 3 (08) : 361 - 363
  • [10] Construction and prediction of protein-protein interaction maps
    Schächter, V
    BIOINFORMATICS AND GENOME ANALYSIS, 2002, 38 : 191 - 220