Synthesis of substituted benzofurans by condensation of arylglyoxals with enols and phenols

被引:0
|
作者
Yu. О. Gorbunov
А. N. Komogortsev
V. S. Mityanov
B. V. Lichitskii
A. A. Dudinov
K. A. Lyssenko
М. М. Krayushkin
机构
[1] Russian Academy of Sciences,N. D. Zelinsky Institute of Organic Chemistry
[2] D. I. Mendeleev University of Chemical Technology of Russia,A. N. Nesmeyanov Institute of Organoelement Compounds
[3] Russian Academy of Sciences,undefined
来源
Russian Chemical Bulletin | 2018年 / 67卷
关键词
multicomponent condensation; arylglyoxals; heterocyclization; enols; pyrid inium salts; 4-dimethylaminopyridine; 4-hydroxy-6-methyl-2; -pyran-2-one; 5,5-dimethylcyclohexane- 1,3-dione; 2-hydroxynaphthalene-1,4-dione; 2-naphthol; 3,4-methylenedioxyphenol; benzofurans;
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学科分类号
摘要
A convenient method for the synthesis of previously unknown substituted 3-hydroxy-5,5- dimethyl-2-(2-arylbenzofuran-3-yl)cyclohex-2-enones, 4-hydroxy-6-methyl-3-(2-arylbenzofuran- 3-yl)-2H-pyran-2-ones, and 2-hydroxy-3-(2-arylbenzofuran-3-yl) naphthoquinones was developed based on the reaction of 3,4-methylenedioxyphenol or 2-naphthol with pyridinium salts obtained by multicomponent condensation of arylglyoxals with carbo- or heterocyclic enols and 4-dimethylaminopyridine.
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页码:504 / 509
页数:5
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