Transcriptional enhancers in development and disease
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作者:
Noboru Jo Sakabe
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机构:University of Chicago,Department of Human Genetics
Noboru Jo Sakabe
Daniel Savic
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机构:University of Chicago,Department of Human Genetics
Daniel Savic
Marcelo A Nobrega
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机构:University of Chicago,Department of Human Genetics
Marcelo A Nobrega
机构:
[1] University of Chicago,Department of Human Genetics
来源:
Genome Biology
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13卷
关键词:
Transcription;
enhancer;
development;
GWAS;
common disease;
D O I:
暂无
中图分类号:
学科分类号:
摘要:
Distal transcription enhancers are cis-regulatory elements that promote gene expression, enabling spatiotemporal control of genetic programs such as those required in metazoan developmental processes. Because of their importance, their disruption can lead to disease.
机构:
Univ London Imperial Coll Sci Technol & Med, Dept Med, London W12 0NN, England
Inst Invest August Pi & Sunyer IDIBAPS, Genom Programming Beta Cells Lab, Barcelona 08036, Spain
CIBER Diabet & Enfermedades Metab Asociadas CIBER, Barcelona 08036, SpainUniv London Imperial Coll Sci Technol & Med, Dept Med, London W12 0NN, England
Miguel-Escalada, Irene
Pasquali, Lorenzo
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机构:
CIBER Diabet & Enfermedades Metab Asociadas CIBER, Barcelona 08036, Spain
Germans Trias & Pujol Univ Hosp & Res Inst, Div Endocrinol, Barcelona 08036, Spain
Josep Carreras Leukaemia Res Inst, Barcelona 08036, SpainUniv London Imperial Coll Sci Technol & Med, Dept Med, London W12 0NN, England
Pasquali, Lorenzo
Ferrer, Jorge
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机构:
Univ London Imperial Coll Sci Technol & Med, Dept Med, London W12 0NN, England
Inst Invest August Pi & Sunyer IDIBAPS, Genom Programming Beta Cells Lab, Barcelona 08036, Spain
CIBER Diabet & Enfermedades Metab Asociadas CIBER, Barcelona 08036, SpainUniv London Imperial Coll Sci Technol & Med, Dept Med, London W12 0NN, England
机构:
NYU, Dept Biol, Dev Syst Training Program, 100 Washington Sq East, New York, NY 10003 USANYU, Dept Biol, Dev Syst Training Program, 100 Washington Sq East, New York, NY 10003 USA
Small, Stephen
Arnosti, David N.
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机构:
Michigan State Univ, Dept Biochem & Mol Biol, E Lansing, MI 48824 USANYU, Dept Biol, Dev Syst Training Program, 100 Washington Sq East, New York, NY 10003 USA
机构:
Univ Texas Southwestern Med Ctr, Cecil H & Ida Green Ctr Reprod Biol Sci, Lab Signaling & Gene Regulat, Dallas, TX USA
Univ Texas Southwestern Med Ctr, Dept Obstet & Gynecol, Div Basic Res, Dallas, TX USA
Univ Texas Southwestern Med Ctr, Dept Obstet & Gynecol, Div Gen Obstet & Gynecol, Dallas, TX USAUniv Texas Southwestern Med Ctr, Cecil H & Ida Green Ctr Reprod Biol Sci, Lab Signaling & Gene Regulat, Dallas, TX USA
Owen, David M.
Kwon, Minjung
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机构:
Univ Texas Southwestern Med Ctr, Cecil H & Ida Green Ctr Reprod Biol Sci, Lab Signaling & Gene Regulat, Dallas, TX USA
Univ Texas Southwestern Med Ctr, Dept Obstet & Gynecol, Div Basic Res, Dallas, TX USAUniv Texas Southwestern Med Ctr, Cecil H & Ida Green Ctr Reprod Biol Sci, Lab Signaling & Gene Regulat, Dallas, TX USA
Kwon, Minjung
Huang, Xuan
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h-index: 0
机构:
Univ Texas Southwestern Med Ctr, Cecil H & Ida Green Ctr Reprod Biol Sci, Lab Signaling & Gene Regulat, Dallas, TX USA
Univ Texas Southwestern Med Ctr, Dept Obstet & Gynecol, Div Basic Res, Dallas, TX USAUniv Texas Southwestern Med Ctr, Cecil H & Ida Green Ctr Reprod Biol Sci, Lab Signaling & Gene Regulat, Dallas, TX USA
Huang, Xuan
Nagari, Anusha
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机构:
Univ Texas Southwestern Med Ctr, Cecil H & Ida Green Ctr Reprod Biol Sci, Lab Signaling & Gene Regulat, Dallas, TX USA
Univ Texas Southwestern Med Ctr, Dept Obstet & Gynecol, Div Basic Res, Dallas, TX USAUniv Texas Southwestern Med Ctr, Cecil H & Ida Green Ctr Reprod Biol Sci, Lab Signaling & Gene Regulat, Dallas, TX USA
Nagari, Anusha
Nandu, Tulip
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机构:
Univ Texas Southwestern Med Ctr, Cecil H & Ida Green Ctr Reprod Biol Sci, Lab Signaling & Gene Regulat, Dallas, TX USA
Univ Texas Southwestern Med Ctr, Dept Obstet & Gynecol, Div Basic Res, Dallas, TX USAUniv Texas Southwestern Med Ctr, Cecil H & Ida Green Ctr Reprod Biol Sci, Lab Signaling & Gene Regulat, Dallas, TX USA
Nandu, Tulip
Kraus, W. Lee
论文数: 0引用数: 0
h-index: 0
机构:
Univ Texas Southwestern Med Ctr, Cecil H & Ida Green Ctr Reprod Biol Sci, Lab Signaling & Gene Regulat, Dallas, TX USA
Univ Texas Southwestern Med Ctr, Dept Obstet & Gynecol, Div Basic Res, Dallas, TX USA
Univ Texas Southwestern Med Ctr Dallas, Cecil H & Ida Green Ctr Reprod Biol Sci, 5323 Harry Hines Blvd, Dallas, TX 75390 USAUniv Texas Southwestern Med Ctr, Cecil H & Ida Green Ctr Reprod Biol Sci, Lab Signaling & Gene Regulat, Dallas, TX USA