Transcriptional enhancers in development and disease

被引:0
|
作者
Noboru Jo Sakabe
Daniel Savic
Marcelo A Nobrega
机构
[1] University of Chicago,Department of Human Genetics
来源
Genome Biology | / 13卷
关键词
Transcription; enhancer; development; GWAS; common disease;
D O I
暂无
中图分类号
学科分类号
摘要
Distal transcription enhancers are cis-regulatory elements that promote gene expression, enabling spatiotemporal control of genetic programs such as those required in metazoan developmental processes. Because of their importance, their disruption can lead to disease.
引用
收藏
相关论文
共 50 条
  • [1] Transcriptional enhancers in development and disease
    Sakabe, Noboru Jo
    Savic, Daniel
    Nobrega, Marcelo A.
    GENOME BIOLOGY, 2012, 13 (01):
  • [2] TRANSCRIPTIONAL ENHANCERS IN ASCIDIAN DEVELOPMENT
    Wang, Wei
    Christiaen, Lionel
    TRANSCRIPTIONAL SWITCHES DURING DEVELOPMENT, 2012, 98 : 147 - 172
  • [3] Transcriptional Enhancers in Animal Development and Evolution
    Levine, Mike
    CURRENT BIOLOGY, 2010, 20 (17) : R754 - R763
  • [4] Transcriptional enhancers: functional insights and role in human disease
    Miguel-Escalada, Irene
    Pasquali, Lorenzo
    Ferrer, Jorge
    CURRENT OPINION IN GENETICS & DEVELOPMENT, 2015, 33 : 71 - 76
  • [5] Transcriptional Enhancers inDrosophila
    Small, Stephen
    Arnosti, David N.
    GENETICS, 2020, 216 (01) : 1 - 26
  • [6] PROKARYOTIC TRANSCRIPTIONAL ENHANCERS
    KUSTU, S
    FASEB JOURNAL, 1995, 9 (06): : A1320 - A1320
  • [7] Ever-Changing Landscapes: Transcriptional Enhancers in Development and Evolution
    Long, Hannah K.
    Prescott, Sara L.
    Wysocka, Joanna
    CELL, 2016, 167 (05) : 1170 - 1187
  • [8] Genomic enhancers in cardiac development and disease
    Anene-Nzelu, Chukwuemeka G.
    Lee, Mick C. J.
    Tan, Wilson L. W.
    Dashi, Albert
    Foo, Roger S. Y.
    NATURE REVIEWS CARDIOLOGY, 2022, 19 (01) : 7 - 25
  • [9] Genomic enhancers in cardiac development and disease
    Chukwuemeka G. Anene-Nzelu
    Mick C. J. Lee
    Wilson L. W. Tan
    Albert Dashi
    Roger S. Y. Foo
    Nature Reviews Cardiology, 2022, 19 : 7 - 25
  • [10] Genome-wide identification of transcriptional enhancers during human placental development and association with function, differentiation, and disease
    Owen, David M.
    Kwon, Minjung
    Huang, Xuan
    Nagari, Anusha
    Nandu, Tulip
    Kraus, W. Lee
    BIOLOGY OF REPRODUCTION, 2023, 109 (06) : 965 - 981