Taming the dragon: genomic biomarkers to individualize the treatment of cancer

被引：0
|
作者：
Ian J Majewski
René Bernards
机构：
[1] Centre for Biomedical Genetics and Cancer Genomics Centre,Division of Molecular Carcinogenesis
[2] The Netherlands Cancer Institute,undefined
来源：
Nature Medicine | 2011年 / 17卷
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The gradual shift from cytotoxic drugs to highly selective, targeted therapeutic agents for cancer requires a parallel effort to characterize cancers at the molecular level to guide the choice of therapy for the individual patient. Here we review the genomic technologies that can be used to develop these drug response indicators, or biomarkers. We also discuss hurdles in their development and the implementation of biomarkers in clinical practice.
引用
收藏
页码：304 / 312
页数：8
相关论文
共 50 条
  • [1] Taming the dragon: genomic biomarkers to individualize the treatment of cancer
    Majewski, Ian J.
    Bernards, Rene
    NATURE MEDICINE, 2011, 17 (03) : 304 - 312
  • [2] Taming the dragon
    Lawrence, R
    EUROPEAN CHEMICAL NEWS, 1998, 69 (1820): : 22 - 22
  • [3] Taming the dragon in Dalmatia
    Anon
    Fire International, 2002, (199):
  • [4] Taming the Pedagogy Dragon
    Riggs, Connie J.
    JOURNAL OF CONTINUING EDUCATION IN NURSING, 2010, 41 (09): : 388 - 388
  • [5] Taming the silicon dragon
    Stevens, F
    Pion, PD
    SEMINARS IN VETERINARY MEDICINE AND SURGERY-SMALL ANIMAL, 1996, 11 (02): : 56 - 62
  • [6] TAMING THE SOFTWARE DRAGON
    STUDT, T
    R&D MAGAZINE, 1993, 35 (14): : 25 - &
  • [7] Taming the Complexity Dragon
    Jo, Henriksen
    JOURNAL OF SIMULATION, 2008, 2 (01) : 3 - 17
  • [8] Taming of the casino dragon
    Jawad, Caroline
    Griffiths, Steve
    COMMUNITY WORK & FAMILY, 2010, 13 (03) : 329 - 347
  • [9] China - Taming the paper dragon
    Papercast, 2003, (193):
  • [10] Time to individualize treatment for adrenocortical cancer?
    Constantine A. Stratakis
    Nature Reviews Endocrinology, 2014, 10 : 76 - 78
12345