Diagnosis and Management of Type II Myocardial Infarction: Increased Demand for a Limited Supply of Evidence

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作者
Nathaniel R. Smilowitz
Becky Naoulou
Steven P. Sedlis
机构
[1] New York University School of Medicine,Division of Cardiology, Department of Medicine
[2] Veteran Affairs Hospital,New York Harbor Health Care System
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关键词
Type 2; Myocardial infarction; Myocardial necrosis; Supply-demand mismatch; Perioperative MI; Endothelial dysfunction; Vasospasm; Anemia; Respiratory failure; Hypoxia; Tachyarrhythmia; Bradyarrhythmia; Hypotension; Hypertension; Shock; Sepsis;
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摘要
Type 2 myocardial infarction (type 2 MI) is defined as myocardial necrosis that results from an imbalance of myocardial oxygen supply and demand. Although type 2 MI is highly prevalent and strongly associated with mortality, the pathophysiology remains poorly understood. Discrepancies in definitions, frequency of screening, diagnostic approaches, and methods of adjudication lead to confusion and misclassification. To date, there is no consensus on the diagnostic criteria for type 2 MI. No guidelines exist for the optimal management of this condition, and further investigation is urgently needed. This review explores the existing evidence on the pathophysiology, diagnosis, prognosis, and management of type 2 MI.
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