Structure Elucidation of Sch 725674 from Aspergillus sp.

被引：0
|
作者：
Shu-Wei Yang
Tze-Ming Chan
Joseph Terracciano
David Loebenberg
Mahesh Patel
Min Chu
机构：
[1] Schering-Plough Research Institute,
[2] Cubist Pharmaceuticals,undefined
[3] Inc.,undefined
来源：
The Journal of Antibiotics | 2005年 / 58卷
关键词：
antifungal; antimicrobial; structure elucidation; Sch 725674;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
A new macrolide Sch725674 (1) was isolated and identified from the culture of an Aspergillus sp. The structure elucidation of 1 was accomplished based on extensive NMR spectroscopic analyses. Compound 1 showed inhibitory activity against Saccharomyces cerevisiae (PM503) and Candida albicans (C43) with MICs of 8 and 32 µg/ml, respectively.
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页码：535 / 538
页数：3
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