Antiangiogenic therapies for high-grade glioma

被引：0
|
作者：
Andrew D. Norden
Jan Drappatz
Patrick Y. Wen
机构：
[1] Brigham and Women's Hospital and Center for Neuro-Oncology,Division of Neuro
[2] Dana-Farber/Brigham and Women's Cancer Center,Oncology, Department of Neurology, Department of Medical Oncology
来源：
Nature Reviews Neurology | 2009年 / 5卷
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摘要：
High-grade gliomas are highly vascularized tumors that represent attractive targets for antiangiogenic therapies. In this article, Norden et al. discuss the rationale for targeting angiogenesis in high-grade gliomas and review the published clinical trial evidence, focusing primarily on therapies that target vascular endothelial growth factor and its receptors.
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页码：610 / 620
页数：10
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