Technical Principles for Protoporphyrin-IX-Fluorescence Guided Microsurgical Resection of Malignant Glioma Tissue

被引：0
|
作者：
W. Stummer
H. Stepp
G. Möller
A. Ehrhardt
M. Leonhard
H. J. Reulen
机构：
[1] Department of Neurosurgery,
[2] Klinikum Grosshadern,undefined
[3] Ludwig-Maximilians-University Munich,undefined
[4] Germany,undefined
[5] Laser Research Laboratory,undefined
[6] Klinikum Grosshadern,undefined
[7] Ludwig-Maximilians-University Munich,undefined
[8] Germany,undefined
[9] Carl Zeiss Development,undefined
[10] Oberkochen,undefined
[11] Germany,undefined
[12] Karl Storz GmbH & Co.,undefined
[13] Tuttlingen,undefined
[14] Germany,undefined
来源：
Acta Neurochirurgica | 1998年 / 140卷
关键词：
Keywords: Aminolevulinic acid; malignant glioma; fluorescence detection; fluorescence microscopy.;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
 Malignant gliomas accumulate fluorescing protoporphyrin IX intracellularly after exposure to 5-aminolevulinic acid, a metabolic precursor of haem. This phenomenon has been exploited for intra-operative identification of residual tumour to enable greater completeness of tumour removal. The present report describes the necessary modifications to the operating microscope to enable microsurgical, fluorescence-guided tumour removal.
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页码：995 / 1000
页数：5
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