Hodgkin’s lymphoma following treatment with etanercept in ankylosing spondylitis

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作者
Kenan Aksu
Ayhan Donmez
Yesim Ertan
Gokhan Keser
Vedat Inal
Gonca Oder
Murat Tombuloglu
Yasemin Kabasakal
Eker Doganavsargil
机构
[1] Ege University School of Medicine Hospital,Internal Medicine
[2] Ege University School of Medicine Hospital,Rheumatology Division
[3] Ege University School of Medicine Hospital,Internal Medicine
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Hodgkin’s lymphoma; Etanercept; Ankylosing spondylitis;
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摘要
It has been well known that anti-TNF drugs might increase lymphoma risk in rheumatoid arthritis (RA), where the rate of lymphoma has already been increased. However, unlike RA, an increased rate of lymphoma has not been reported in ankylosing spondylitis (AS). Hereby, we present a case with AS developing Hodgkin’s lymphoma (HL) following 6 months of etanercept treatment. Pathological analysis revealed mixed cellular type of HL. Although we report a single case, it should be kept in mind that anti-TNF drugs might cause lymphoma development not only in RA, but also in AS.
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