Stage-dependent BDNF serum concentrations in Alzheimer’s disease

被引：0
|
作者：
C. Laske
E. Stransky
T. Leyhe
G. W. Eschweiler
A. Wittorf
E. Richartz
M. Bartels
G. Buchkremer
K. Schott
机构：
[1] Department of Psychiatry and Psychotherapy,
[2] Geriatric Centrum,undefined
[3] University of Tuebingen,undefined
来源：
Journal of Neural Transmission | 2006年 / 113卷
关键词：
Keywords: Alzheimer’s disease (AD), early stages, late stages, BDNF, serum, CSF, healthy controls, MMSE.;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Alzheimer’s disease (AD) is characterized by cognitive decline and loss of neurons in specific brain regions. Recent findings have suggested an involvement of brain-derived neurotrophic factor (BDNF) in the pathogenesis of AD. BDNF is an endogenous protein involved in the maintenance of neuronal function, synaptic plasticity and structural integrity in the adult brain.
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页码：1217 / 1224
页数：7
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