Integrative genomic analyses reveal clinically relevant long noncoding RNAs in human cancer

被引：0
|
作者：
Zhou Du
Teng Fei
Roel G W Verhaak
Zhen Su
Yong Zhang
Myles Brown
Yiwen Chen
X Shirley Liu
机构：
[1] School of Life Sciences and Technology,Department of Bioinformatics
[2] Tongji University,Department of Medical Oncology
[3] Center for Functional Cancer Epigenetics,Department of Medicine
[4] Dana-Farber Cancer Institute,Department of Biostatistics and Computational Biology
[5] Dana-Farber Cancer Institute,Department of Bioinformatics and Computational Biology, Division of Quantitative Sciences
[6] Brigham and Women's Hospital and Harvard Medical School,undefined
[7] Dana-Farber Cancer Institute and Harvard School of Public Health,undefined
[8] The University of Texas MD Anderson Cancer Center,undefined
[9] College of Biological Sciences,undefined
[10] China Agriculture University,undefined
来源：
Nature Structural & Molecular Biology | 2013年 / 20卷
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学科分类号：
摘要：
By integrating the expression profiles of long noncoding RNAs (lncRNAs) with clinical outcome and somatic copy-number alteration, the authors identified new lncRNAs that are associated with certain cancer subtypes and clinical prognoses. Experimental validation of the prostate cancer cell growth dependence of two new lncRNAs demonstrates the power of this approach for discovering disease-related lncRNAs.
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页码：908 / 913
页数：5
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