Pertactin antigens extracted from Bordetella pertussis and Bordetella bronchiseptica differ in the isoelectric point

被引：0
|
作者：
Cristina Pagliaccia
Roberto Manetti
R. Rappuoli
机构：
[1] IRIS,
[2] The Chiron Vaccines Immunobiological Research Institute,undefined
[3] Via Fiorentina 1,undefined
[4] 53100 Siena,undefined
[5] Italy Tel. +39-577-243414; Fax +39-577-243564 email: rappuoli@iris02.biocine.it,undefined
来源：
Archives of Microbiology | 1997年 / 168卷
关键词：
Key words Pertactin; 69K antigen; Bordetella; pertussis; Bordetella bronchiseptica; Pertussis vaccine; Acellular pertussis vaccine;
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学科分类号：
摘要：
Pertactin, which is a membrane-associated antigen of Bordetella pertussis and which is present in many acellular vaccines against whooping cough, has been reported to be similar to the homologous protein in Bordetella bronchiseptica. By running parallel experiments using proteins derived from the two species, we show that the isoelectric point of pertactin from B. pertussis is lower than reported and clearly distinguishable from the homologous protein of B. bronchiseptica.
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页码：437 / 440
页数：3
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