CYP1B1-catalyzed 4-OHE2 promotes the castration resistance of prostate cancer stem cells by estrogen receptor α-mediated IL6 activation

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作者
Qimei Lin
Jiasong Cao
Xiaoling Du
Kuo Yang
Xu Yang
Zhixian Liang
Jiandang Shi
Ju Zhang
机构
[1] Nankai University,Department of Biochemistry and Molecular Biology, College of Life Sciences, Bioactive Materials Key Lab of the Ministry of Education
[2] Nankai University,Tianjin Key Lab of Human Development and Reproductive Regulation, Tianjin Central Hospital of Obstetrics and Gynecology
[3] Second Hospital of Tianjin Medical University,Department of Urology
来源
Cell Communication and Signaling | / 20卷
关键词
CYP1B1; 4-OHE2; ERα; IL6-STAT3 pathway; PCSC; Castration-resistant prostate cancer;
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