Study of the interaction between HSA and oligo-DNA using total internal reflection ellipsometry

被引：0
|
作者：
Y. W. Jung
J. S. Byun
Y. D. Kim
D. Hemzal
J. Humliček
机构：
[1] Kyung Hee University,Nano
[2] Masaryk University,Optical Property Laboratory and Department of Physics
来源：
Journal of the Korean Physical Society | 2012年 / 60卷
关键词：
Ellipsometry; Total internal reflection; HSA; DNA; Biosensors;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Techniques of quantitative analysis are very important for studies of the interactions between bio-molecules in the field of biotechnology and drug development. The total internal reflection ellipsometry system (TIRE) is an attractive label-free procedure for the quantitative analysis of biomolecules because it combines the analytic ability of ellipsometry and the high surface sensitivity of surface plasmon resonance. In this work, we have used TIRE to study the optical properties of an aquatic monolayer of human serum albumin (HSA) and oligo-DNA. Also, we have monitored the adsorption and the interaction processes of protein layers.
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页码：1288 / 1291
页数：3
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