Treatment with Ebastine Changes Expression of Histamine H1 and H2 Receptor mRNA on Peripheral Blood Mononuclear Cells

被引：0
|
作者：
Teresa Zak-Nejmark
Jozef Malolepszy
Maria Kraus-Filarska
Tadeusz Dobosz
Marek Jutel
Grazyna Nadobna
Anna Jonkisz
机构：
[1] Wroclaw Medical University,Department of Internal Medicine and Allergology
[2] Wroclaw Medical University,Institute of Forensic Medicine
来源：
Clinical Drug Investigation | 2002年 / 22卷
关键词：
Histamine; Peripheral Blood Mononuclear Cell; Histamine Receptor; Allergic Symptom; Ebastine;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Background: Histamine H1 and H2 receptors both belong to a family of G protein-coupled receptors that often show opposite actions on cell activity. Ebastine, a piperidine derivative, and its active metabolite, carebastine, are very potent second-generation histamine H1 receptor antagonists.
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页码：25 / 30
页数：5
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