Lamellar macular hole following intravitreal pegaptanib sodium (Macugen) injection for diabetic macular edema.

被引：6
|
作者：
Querques G. [1 ]
Bux A.V. [1 ]
Iaculli C. [1 ]
Noci N.D. [1 ]
机构：
[1] Department of Ophthalmology, Ospedali Riuniti, University of Foggia, Foggia
来源：
International Ophthalmology | 2011年 / 31卷 / 6期
关键词：
Diabetic macular edema; Lamellar macular hole; Macugen; Optical coherence tomography; Pegaptanib sodium;
D O I：
10.1007/s10792-011-9493-1
中图分类号：
学科分类号：
摘要：
To report on a patient who developed a lamellar macular hole 1 month after an intravitreal pegaptanib sodium injection. Interventional case report. A 66 year old patient developed a lamellar macular hole 1 month after an intravitreal pegaptanib sodium injection for diabetic macular edema (DME). The pathogenesis of the lamellar macular hole in our case can be attributed to the intravitreal injection that may have induced vitreous incarceration, causing vitreoretinal traction at the macula and development of a lamellar macular hole. Alternatively or in association, pegaptanib itself may have caused the lamellar macular hole by inducing sudden reduction of the DME and exacerbation of tangential traction of the posterior vitreous on the overlying macular retina. Lamellar macular hole seems to be a potential complication of pegaptanib injection even in patients without pretreatment clinically detectable vitreomacular traction.
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页码：525 / 527
页数：2
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