Protective effect of placenta extracts against nitrite-induced oxidative stress in human erythrocytes

被引:0
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作者
Svitlana Rozanova
Yana Cherkashina
Svitlana Repina
Katherina Rozanova
Oleg Nardid
机构
[1] NAS of Ukraine,Department of Cryobiophysics, Institute for Problems of Cryobiology and Cryomedicine
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关键词
Human placenta extract; Protein; Antioxidant activity; Oxidative stress; Nitrite; Erythrocyte; Methemoglobin; Cytosol; Freezing; Thawing;
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学科分类号
摘要
Aqueous-saline human placenta extract (HPE) is known to possess antioxidant activity due to the high concentration of bioactive substances. This fact allows its application in clinical practice in order to treat oxidation-induced diseases. Extract antioxidant activity is mainly conditioned by proteins. Freezing of extracts has been shown to lead to their antioxidant activity increasing due to protein conformation changes.
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页码:240 / 248
页数:8
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