Oral versus Topical NSAIDs in Rheumatic DiseasesA Comparison

被引：0
|
作者：
Catherine A. Heyneman
Cara Lawless-Liday
Geoffrey C. Wall
机构：
[1] Idaho State University College of Pharmacy,Department of Pharmacy Practice and Administrative Sciences
[2] Drake University College of Pharmacy,Department of Pharmacy Practice
[3] Idaho State University College of Pharmacy,undefined
来源：
Drugs | 2000年 / 60卷
关键词：
Ibuprofen; Synovial Fluid; Piroxicam; Topical Administration; Rheumatic Disorder;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Nonsteroidal anti-inflammatory drugs (NSAIDs) are among the most commonly prescribed drugs worldwide and are responsible for approximately one-quarter of all adverse drug reaction reports. NSAIDs are widely prescribed for patients with rheumatic disease — a population at increased risk for serious gastrointestinal (GI) complications. Topical administration of NSAIDs offers the advantage of local, enhanced drug delivery to affected tissues with a reduced incidence of systemic adverse effects, such as peptic ulcer disease and GI haemorrhage.
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页码：555 / 574
页数：19
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