Microwave-Assisted Synthesis of Novel Spirochromanone–Aurone Hybrids and Their Antimicrobial Activity

被引:0
|
作者
N. Ramana Kishore
D. Ashok
M. Sarasija
N. Y. S. Murthy
机构
[1] Vishnu Chemicals Ltd.,Green and Medicinal Chemistry Laboratory, Department of Chemistry
[2] Osmania University,Department of Chemistry
[3] Satavahana University,Department of Chemistry
[4] Anurag group of Institutions,undefined
来源
Russian Journal of General Chemistry | 2018年 / 88卷
关键词
spiro chromanones; chalcones; aurones; antimicrobial activity;
D O I
暂无
中图分类号
学科分类号
摘要
New chromanone and aurone hybrids have been synthesized by conventional and microwave induced methods from substituted (E)-7-hydroxy-6-[3-(p-tolyl)acryloyl]spiro[chroman-2,1'-cyclohexan]-4-one with high yields. Structures of the synthesized compounds have been elucidated from IR, 1H and 13C NMR, and mass spectra. All newly synthesized compounds were tested in vitro for their antimicrobial activity. Methoxysubstituted spirochromanones revealed the best antimicrobial profile.
引用
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页码:1015 / 1019
页数:4
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