Ontogeny, differentiation and growth of the endocrine pancreas

被引：0
|
作者：
Jochen Peters
Anja Jürgensen
G. Klöppel
机构：
[1] Department of Pathology,
[2] University of Kiel,undefined
[3] Michaelisstrasse 11,undefined
[4] 24105 Kiel,undefined
[5] Germany e-mail: gkloeppel@path.uni-kiel.de Tel.: +49-431-5973400,undefined
[6] Fax: +49-431-5973462,undefined
来源：
Virchows Archiv | 2000年 / 436卷
关键词：
Key words Endocrine pancreas; Morphogenesis; Differentiation; Growth;
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摘要：
The pancreas develops from the primitive foregut endoderm, which differentiates into ductal, acinar and endocrine cells. This complex process is probably replicated in the adult pancreas when endocrine cell renewal is required, as may be the case in diabetes mellitus. This review describes what is known about the morphogenesis of the endocrine pancreas during ontogeny and the mechanisms regulating its differentiation and growth.
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页码：527 / 538
页数：11
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