The association between body size, prostate volume and prostate-specific antigen

被引：0
|
作者：
J H Fowke
S S Motley
M S Cookson
R Concepcion
S S Chang
M L Wills
J A Smith
机构：
[1] Vanderbilt Epidemiology Center,Division of Internal Medicine and Public Health
[2] Vanderbilt University Medical Center,Department of Urologic Surgery
[3] Vanderbilt University Medical Center,Department of Pathology
[4] Urology Associates,undefined
[5] Vanderbilt University Medical Center,undefined
来源：
Prostate Cancer and Prostatic Diseases | 2007年 / 10卷
关键词：
obesity; prostate volume; height; PSA; benign prostatic hyperplasia;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Increasing prostate volume contributes to urinary tract symptoms and may obscure prostate cancer detection. We investigated the association between obesity and prostate volume, prostate-specific antigen (PSA) and PSA density among 753 men referred for prostate biopsy. Among men with a negative biopsy, prostate volume significantly increased approximately 25% from the lowest to highest body mass index (BMI), waist or hip circumference or height categories. PSA was 0.7 ng/ml lower with a high waist-to-hip ratio. These associations were less consistent among subjects diagnosed with high-grade prostatic intraepithelial neoplasia or cancer. Our data suggest that obesity and height are independently associated with prostate volume.
引用
收藏
页码：137 / 142
页数：5
相关论文
共 50 条
  • [1] The association between body size, prostate volume and prostate-specific antigen
    Fowke, J. H.
    Motley, S. S.
    Cookson, M. S.
    Concepcion, R.
    Chang, S. S.
    Wills, M. L.
    Smith, J. A., Jr.
    PROSTATE CANCER AND PROSTATIC DISEASES, 2007, 10 (02) : 137 - 142
  • [2] RELATIONSHIP BETWEEN PROSTATE-SPECIFIC ANTIGEN, PROSTATE VOLUME AND AGE IN THE BENIGN PROSTATE
    COLLINS, GN
    LEE, RJ
    MCKELVIE, GB
    ROGERS, ACN
    HEHIR, M
    BRITISH JOURNAL OF UROLOGY, 1993, 71 (04): : 445 - 450
  • [3] Association between obesity, prostate-specific antigen level and prostate-specific antigen density in men with a negative prostate biopsy
    Kim, Jae Heon
    Lee, Sang Wook
    Kim, Jae Ho
    Yang, Hee Jo
    Doo, Seung Whan
    Yoon, Jong Hyun
    Kim, Doo Sang
    Yang, Won Jae
    Lee, Kwang Woo
    Kim, Jun Mo
    Lee, Changho
    Kwon, Soon-Sun
    JOURNAL OF INTERNATIONAL MEDICAL RESEARCH, 2014, 42 (03) : 821 - 827
  • [4] RELATIONSHIP BETWEEN SERUM PROSTATE-SPECIFIC ANTIGEN CONCENTRATION AND PROSTATE VOLUME
    YU, HJ
    CHIANG, GJ
    CHIU, TY
    LAI, MK
    JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION, 1995, 94 (11) : 666 - 670
  • [5] Association between genetic polymorphisms in the prostate-specific antigen gene promoter and serum prostate-specific antigen levels
    Cramer, SD
    Chang, BL
    Rao, A
    Hawkins, GA
    Zheng, SL
    Wade, WN
    Cooke, RT
    Thomas, LN
    Bleecker, ER
    Catalona, WJ
    Sterling, DA
    Meyers, DA
    Ohar, J
    Xu, JF
    JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2003, 95 (14): : 1044 - 1053
  • [6] Relationship between prostate volume, prostate-specific antigen nadir, and biochemical control
    Kaminski, JM
    Hanlon, AL
    Horwitz, EM
    Pinover, WH
    Mitra, RK
    Hanks, GE
    INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2002, 52 (04): : 888 - 892
  • [7] Free prostate-specific antigen outperforms total prostate-specific antigen as a predictor of prostate volume in patients without prostate cancer
    Avci, Sinan
    Onen, Efe
    Caglayan, Volkan
    Kilic, Metin
    Sambel, Murat
    Oner, Sedat
    ARCHIVIO ITALIANO DI UROLOGIA E ANDROLOGIA, 2020, 92 (01) : 1 - 6
  • [8] Association of Diabetes and Body Mass Index with Levels of Prostate-Specific Antigen: Implications for Correction of Prostate-Specific Antigen Cutoff Values?
    Mueller, Heiko
    Raum, Elke
    Rothenbacher, Dietrich
    Stegmaier, Christa
    Brenner, Hermann
    CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 2009, 18 (05) : 1350 - 1356
  • [9] Complexed prostate-specific antigen and the "prostate-specific antigen gap"
    Croal, BL
    Mitchell, I
    Dickie, A
    Duff, PA
    Cohen, NP
    Ross, IS
    CLINICAL CHEMISTRY, 1999, 45 (11) : 2040 - 2040
  • [10] Relationships between prostate-specific antigen and prostate volume in black and white men with benign prostate biopsies
    Fowler, JE
    Bigler, SS
    Kilambi, NK
    Land, SA
    UROLOGY, 1999, 53 (06) : 1175 - 1178
12345