Aromatic polyketides from a sponge-derived fungus Metarhizium anisopliae mxh-99 and their antitubercular activities

被引：0
|
作者：
Xianglan Kong
Xinhua Ma
Yunying Xie
Shengxin Cai
Tianjiao Zhu
Qianqun Gu
Dehai Li
机构：
[1] School of Medicine and Pharmacy,Key Laboratory of Marine Drugs, Chinese Ministry of Education
[2] Ocean University of China,Institute of Medicinal Biotechnology
[3] Chinese Academy of Medical Sciences & Peking Union Medical College,undefined
来源：
Archives of Pharmacal Research | 2013年 / 36卷
关键词：
Sponge-derived fungus; Secondary metabolites; Naphtho-γ-pyrones; Diphenyl ethers; Antitubercular activity;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
In our screening for antitubercular agents, five naphtho-γ-pyrones including two new naphtho-γ-pyrones glycosides, indigotides G and H (1 and 2), and two diphenyl ethers were isolated from the extract of a sponge-derived fungus Metarhizium anisopliae mxh-99. Their structures were established on the basis of chemical and spectroscopic evidence. The antitubercular activities of all the compounds were evaluated against Mycobacterium phlei. The known isochaetochromin B2 (6) and ustilaginoidin D (7) exhibited the highest activity with MICs 50.0 μg/mL.
引用
收藏
页码：739 / 744
页数：5
相关论文
共 50 条
  • [1] Aromatic polyketides from a sponge-derived fungus Metarhizium anisopliae mxh-99 and their antitubercular activities
    Kong, Xianglan
    Ma, Xinhua
    Xie, Yunying
    Cai, Shengxin
    Zhu, Tianjiao
    Gu, Qianqun
    Li, Dehai
    ARCHIVES OF PHARMACAL RESEARCH, 2013, 36 (06) : 739 - 744
  • [2] Cytoprotective Polyketides from Sponge-Derived Fungus Lopadostoma pouzarii
    Phan Thi Hoai Trinh
    Yurchenko, Anton N.
    Khmel, Olga O.
    Trang Vo Thi Dieu
    Ngo Thi Duy Ngoc
    Girich, Elena, V
    Menshov, Alexander S.
    Kim, Natalya Y.
    Chingizova, Ekaterina A.
    Tran Thi Thanh Van
    Lee, Jong Seok
    Lee, Hyi-Seung
    Yurchenko, Ekaterina A.
    MOLECULES, 2022, 27 (21):
  • [3] Two new aromatic polyketides from a sponge-derived Fusarium
    Sibero, Mada Triandala
    Zhou, Tao
    Fukaya, Keisuke
    Urabe, Daisuke
    Radjasa, Ocky K. Karna
    Sabdono, Agus
    Trianto, Agus
    Igarashi, Yasuhiro
    BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY, 2019, 15 : 2941 - 2947
  • [4] Peptides and polyketides isolated from the marine sponge-derived fungus Aspergillus terreus SCSIO 41008
    LUO Xiao-Wei
    LIN Yun
    LU Yong-Jun
    ZHOU Xue-Feng
    LIU Yong-Hong
    Chinese Journal of Natural Medicines, 2019, 17 (02) : 149 - 154
  • [5] Peptides and polyketides isolated from the marine sponge-derived fungus Aspergillus terreus SCSIO 41008
    Luo Xiao-Wei
    Lin Yun
    Lu Yong-Jun
    Zhou Xue-Feng
    Liu Yong-Hong
    CHINESE JOURNAL OF NATURAL MEDICINES, 2019, 17 (02) : 149 - 154
  • [6] Antibacterial Polyketides from Antarctica Sponge-Derived Fungus Penicillium sp. HDN151272
    Shah, Mudassir
    Sun, Chunxiao
    Sun, Zichao
    Zhang, Guojian
    Che, Qian
    Gu, Qianqun
    Zhu, Tianjiao
    Li, Dehai
    MARINE DRUGS, 2020, 18 (02)
  • [7] Three new polyketides from the marine sponge-derived fungus Trichoderma sp SCSIO41004
    Pang, Xiaoyan
    Lin, Xiuping
    Tian, Yongqi
    Liang, Rui
    Wang, Junfeng
    Yang, Bin
    Zhou, Xuefeng
    Kaliyaperumal, Kumaravel
    Luo, Xiaowei
    Tu, Zhengchao
    Liu, Yonghong
    NATURAL PRODUCT RESEARCH, 2018, 32 (01) : 105 - 111
  • [8] Phenylspirodrimanes with Anti-HIV Activity from the Sponge-Derived Fungus Stachybotrys chartarum MXH-X73
    Ma, Xinhua
    Lo, Letao
    Zhu, Tianjiao
    Ba, Mingyu
    Li, Guoqiang
    Gu, Qianqun
    Guo, Ying
    Li, Dehai
    JOURNAL OF NATURAL PRODUCTS, 2013, 76 (12): : 2298 - 2306
  • [9] New Alkaloids and Polyketides from the Marine Sponge-Derived Fungus Penicillium sp. SCSIO41015
    Pang, Xiaoyan
    Cai, Guodi
    Lin, Xiuping
    Salendra, Limbadri
    Zhou, Xuefeng
    Yang, Bin
    Wang, Junjian
    Wang, Junfeng
    Xu, Shihai
    Liu, Yonghong
    MARINE DRUGS, 2019, 17 (07):
  • [10] Cytotoxic Polyketides from the Marine Sponge-Derived Fungus Pestalotiopsis heterocornis XWS03F09
    Lei, Hui
    Lei, Jing
    Zhou, Xuefeng
    Hu, Mei
    Niu, Hong
    Song, Can
    Chen, Siwei
    Liu, Yonghong
    Zhang, Dan
    MOLECULES, 2019, 24 (14):
12345