A case of methyl ethyl ketone peroxide poisoning and a review of complications and their management

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作者
Isurujith K. Liyanage
Mitrakrishnan R. Navinan
A C A Pathirana
H R I S Herath
Jevon Yudhishdran
Nilesh Fernandopulle
Aruna Kulatunga
机构
[1] National Hospital of Sri Lanka,Department of Pharmacology, Faculty of Medical Sciences
[2] University of Sri Jayewardenepura,undefined
关键词
Methyl Ethyl Ketone Peroxide; Management of corrosive gastrointestinal burns; Occupational safety;
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摘要
Methyl Ethyl Ketone Peroxide (MEKP) is a highly toxic clear liquid used as a solvent. It is a strong oxidizing agent and a corrosive. Acute and chronic toxicity can occur as an occupational hazard. Ingestion is associated with corrosive burns leading to stricture formation, inhalational pneumonitis, acidosis, liver failure and renal failure. In this paper we present a case of a young patient who intentionally ingested MEKP. The patient developed multiple complications including proximal intestinal obstruction, acidosis and acute kidney injury. He was managed conservatively and recovered after a prolonged hospital stay. He had multiple inflammatory strictures on esophageal endoscopy, which improved over 3–6 moths.
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