Mechanism of the thermogenic effect of Metabolite 2 (BTS 54 505), a major pharmacologically active metabolite of the novel anti-obesity drug, sibutramine

被引:0
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作者
Y-L Liu
DJ Heal
MJ Stock
机构
[1] St George's Hospital Medical School,Department of Physiology
[2] University of London,undefined
[3] Knoll Ltd Research and Development,undefined
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关键词
sibutramine; BTS 54 505; thermogenesis; colonic temperature; food intake;
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摘要
OBJECTIVE: To investigate the pharmacological mechanisms underlying the induction of thermogenesis by Metabolite 2 (M2; BTS 54 505), a major pharmacologically active metabolite of the anti-obesity drug, sibutramine.
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页码:1245 / 1253
页数:8
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