Synthesis of 2,3-dihydroquinazolin-4(1H)-ones via one-pot three-component reaction catalyzed by l-pyrrolidine-2-carboxylic acid-4-hydrogen sulfate (supported on silica gel) as novel and recoverable catalyst

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作者
Arash Ghorbani-Choghamarani
Parisa Zamani
机构
[1] Ilam University,Department of Chemistry, Faculty of Science
关键词
2,3-Dihydroquinazolin-4(1H)-one; Isatoic anhydride; -Pyrrolidine-2-carboxylic acid-4-hydrogen sulfate; Multi-component reaction; Catalysis;
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摘要
A wide variety of 2,3-dihydroquinazolin-4(1H)-ones has been prepared via one-pot three-component condensation of isatoic anhydride, aldehydes and primary amines or ammonium acetate in the presence of a catalytic amounts of l-pyrrolidine-2-carboxylic acid-4-hydrogen sulfate (supported on silica gel), as green, non-toxic and reusable catalyst, in water at 80 °C.
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页码:607 / 613
页数:6
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